Heart failure (HF) is a significant cause of morbidity and mortality worldwide. Circulating
biomarkers reflecting pathophysiological pathways involved in HF development and …

Diabetes mellitus has been recognised as one of the four major non-communicable
diseases that demands urgent attention from all key shareholders globally in an effort to …

Most older individuals develop inflammageing, a condition characterized by elevated levels
of blood inflammatory markers that carries high susceptibility to chronic morbidity, disability …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Inflammation is a biological response of the immune system that can be triggered by a
variety of factors, including pathogens, damaged cells and toxic compounds. These factors …

Flavonoids are plant‐derived dietary components with a substantial impact on human
health. Research has expanded massively since it began in the 1930s, and the complex …

It is well documented that the rate of aging can be slowed, but it remains unclear to which
extent aging-associated conditions can be reversed. How the interface of immunity and …

The vascular cellular adhesion molecule-1 (VCAM-1) is a protein that canonically
participates in the adhesion and transmigration of leukocytes to the interstitium during …

How might contact with nature promote human health? Myriad studies have linked the two;
at this time the task of identifying the mechanisms underlying this link is paramount. This …

Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …