The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden

DF Meaney, B Morrison… - Journal of …, 2014 - asmedigitalcollection.asme.org
Traumatic brain injury (TBI) is a significant public health problem, on pace to become the
third leading cause of death worldwide by 2020. Moreover, emerging evidence linking …

Neuropathology of explosive blast traumatic brain injury

J Magnuson, F Leonessa, GSF Ling - Current neurology and neuroscience …, 2012 - Springer
During the conflicts of the Global War on Terror, which are Operation Enduring Freedom
(OEF) in Afghanistan and Operation Iraqi Freedom (OIF), there have been over a quarter of a …

An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain

X Li, Z Zhou, S Kleiven - Biomechanics and modeling in mechanobiology, 2021 - Springer
Finite element head (FE) models are important numerical tools to study head injuries and
develop protection systems. The generation of anatomically accurate and subject-specific …

[HTML][HTML] A study of the response of the human cadaver head to impact

WN Hardy, MJ Mason, CD Foster, CS Shah… - Stapp car crash …, 2007 - ncbi.nlm.nih.gov
High-speed biplane x-ray and neutral density targets were used to examine brain
displacement and deformation during impact. Relative motion, maximum principal strain …

Deformation of the human brain induced by mild angular head acceleration

AA Sabet, E Christoforou, B Zatlin, GM Genin… - Journal of …, 2008 - Elsevier
Deformation of the human brain was measured in tagged magnetic resonance images (MRI)
obtained dynamically during angular acceleration of the head. This study was undertaken to …

In vivo estimates of axonal stretch and 3D brain deformation during mild head impact

AK Knutsen, AD Gomez, M Gangolli, WT Wang… - Brain multiphysics, 2020 - Elsevier
The rapid deformation of brain tissue in response to head impact can lead to traumatic brain
injury. In vivo measurements of brain deformation during non-injurious head impacts are …

Development and validation of an advanced anisotropic visco-hyperelastic human brain FE model

D Sahoo, C Deck, R Willinger - Journal of the mechanical behavior of …, 2014 - Elsevier
This paper proposes the implementation of fractional anisotropy and axonal fiber orientation
from diffusion tensor imaging (DTI) of 12 healthy patients into an existing human FE head …

Mathematical models of blast-induced TBI: current status, challenges, and prospects

RK Gupta, A Przekwas - Frontiers in neurology, 2013 - frontiersin.org
Blast-induced traumatic brain injury (TBI) has become a signature wound of recent military
activities and is the leading cause of death and long-term disability among US soldiers. The …

Relative brain displacement and deformation during constrained mild frontal head impact

Y Feng, TM Abney, RJ Okamoto… - Journal of the …, 2010 - royalsocietypublishing.org
This study describes the measurement of fields of relative displacement between the brain
and the skull in vivo by tagged magnetic resonance imaging and digital image analysis …

Displacement-and strain-based discrimination of head injury models across a wide range of blunt conditions

W Zhao, S Ji - Annals of biomedical engineering, 2020 - Springer
Successful validation of a head injury model is critical to ensure its biofidelity. However,
there is an ongoing debate on what experimental data are suitable for model validation …