Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma

KMM Espíndola, RG Ferreira, LEM Narvaez… - Frontiers in …, 2019 - frontiersin.org
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …

Biochanin A: A novel bioactive multifunctional compound from nature

A Sarfraz, M Javeed, MA Shah, G Hussain… - Science of the Total …, 2020 - Elsevier
Natural products (NPs) will continue to serve humans as matchless source of novel drug
leads and an inspiration for the synthesis of non-natural drugs. As our scientific …

Exosomes as drug delivery vehicles for Parkinson's disease therapy

MJ Haney, NL Klyachko, Y Zhao, R Gupta… - Journal of controlled …, 2015 - Elsevier
Exosomes are naturally occurring nanosized vesicles that have attracted considerable
attention as drug delivery vehicles in the past few years. Exosomes are comprised of natural …

Biochanin-A ameliorates pulmonary fibrosis by suppressing the TGF-β mediated EMT, myofibroblasts differentiation and collagen deposition in in vitro and in vivo …

SB Andugulapati, K Gourishetti, SK Tirunavalli… - Phytomedicine, 2020 - Elsevier
Abstract Background: Idiopathic Pulmonary Fibrosis (IPF) is a progressive inflammatory
disorder driven by a fibrotic cascade of events such as epithelial to mesenchymal transition …

Perspectives regarding the role of biochanin A in humans

C Yu, P Zhang, L Lou, Y Wang - Frontiers in pharmacology, 2019 - frontiersin.org
Biochanin A (BCA) is an isoflavone mainly found in red clover with poor solubility and oral
absorption that is known to have various effects, including anti-inflammatory, estrogen-like …

Neuroprotection impact of biochanin A against pentylenetetrazol-kindled mice: targeting NLRP3 inflammasome/TXNIP pathway and autophagy modulation

RM El-Sayed, MN Fawzy, HF Zaki… - International …, 2023 - Elsevier
Recurrent seizures characterize epilepsy, a complicated and multifaceted neurological
disease. Several neurological alterations, such as cell death and the growth of gorse fibers …

Walnut (Juglans regia) Peptides Reverse Sleep Deprivation-Induced Memory Impairment in Rat via Alleviating Oxidative Stress

S Wang, G Su, Q Zhang, T Zhao, Y Liu… - Journal of agricultural …, 2018 - ACS Publications
The aim of this study was to determine the neuroprotective effects of walnut protein
hydrolysates (WPH) against memory deficits induced by sleep deprivation (SD) in rat and …

Arctium lappa L. roots ameliorates cerebral ischemia through inhibiting neuronal apoptosis and suppressing AMPK/mTOR-mediated autophagy

Y Yang, H Gao, W Liu, X Liu, X Jiang, X Li, Q Wu, Z Xu… - Phytomedicine, 2021 - Elsevier
Background Arctium lappa L. roots are very popular cultivated vegetables, which possesses
various pharmacological activities. Our previous studies have demonstrated that Arctium …

Protective effects of functional foods against Parkinson's disease: A narrative review on pharmacology, phytochemistry, and molecular mechanisms

M Iranshahy, B Javadi, A Sahebkar - Phytotherapy research, 2022 - Wiley Online Library
Abstract In Persian Medicine (PM), PD (brain‐based tremor) is a known CNS disorder with
several therapeutic and preventive options. In their medical textbooks and pharmacopeias …

Molecular mechanisms underlying the potential neuroprotective effects of Trifolium pratense and its phytoestrogen‐isoflavones in neurodegenerative disorders

AS Al‐Shami, AE Essawy… - Phytotherapy …, 2023 - Wiley Online Library
Neurodegenerative disorders are heterogeneous, debilitating, and incurable groups of brain
disorders that have common features including progressive degeneration of the structure …