[HTML][HTML] Perivascular adipose tissue: Fine-tuner of vascular redox status and inflammation

CK Cheng, H Ding, M Jiang, H Yin, M Gollasch… - Redox Biology, 2023 - Elsevier
Perivascular adipose tissue (PVAT) refers to the aggregate of adipose tissue surrounding
the vasculature, exhibiting the phenotypes of white, beige and brown adipocytes. PVAT has …

The role of polyphenol in modulating associated genes in diabetes-induced vascular disorders

NA Mohd Nor, SB Budin, S Zainalabidin, J Jalil… - International Journal of …, 2022 - mdpi.com
Diabetes-induced vascular disorder is considered one of the deadly risk factors among
diabetic patients that are caused by persistent hyperglycemia that eventually leads to …

Role of dysfunctional peri-organ adipose tissue in metabolic disease

K Zhang, J Zhang, C Kan, H Tian, Y Ma, N Huang… - Biochimie, 2023 - Elsevier
Metabolic disease is a complex disorder defined by a group with interrelated factors. There
is growing evidence that obesity can lead to a variety of metabolic diseases, including …

Nicotine Impairs the Anti-Contractile Function of Perivascular Adipose Tissue by Inhibiting the PPARγ–Adiponectin–AdipoR1 Axis

AZ Abd Rami, A Aminuddin, AA Hamid… - International Journal of …, 2023 - mdpi.com
Nicotine is an addictive compound found in cigarette smoke that leads to vascular
dysfunction and cardiovascular diseases. Perivascular adipose tissue (PVAT) exerts an anti …

The Role of Perivascular Adipose Tissue in the Pathogenesis of Endothelial Dysfunction in Cardiovascular Diseases and Type 2 Diabetes Mellitus

A Valentini, C Cardillo, D Della Morte, M Tesauro - Biomedicines, 2023 - mdpi.com
Cardiovascular diseases (CVDs) and type 2 diabetes mellitus (T2DM) are two of the four
major chronic non-communicable diseases (NCDs) representing the leading cause of death …

Three polymethoxyflavones from the peel of Citrus reticulata “Chachi” inhibits oxidized low-density lipoprotein-induced macrophage-derived foam cell formation

PL Liang, QW Liang, PW He, XL Chen, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Foam cell formation is the hallmark of the development and progression of atherosclerosis.
The aim of this study was to investigate the regulatory effects of three polymethoxyflavones …

Fat and inflammation: adipocyte-myeloid cell crosstalk in atherosclerosis

AM Mazitova, AC Márquez-Sánchez… - Frontiers in …, 2023 - frontiersin.org
Adipose tissue inflammation has been implicated in various chronic inflammatory diseases
and cancer. Perivascular adipose tissue (PVAT) surrounds the aorta as an extra layer and …

Omentin-1 and diabetes: more evidence but far from enough

J Xu, M Li, X Jiang, Y Wang, H Ma, Y Zhou… - … of Physiology and …, 2024 - Taylor & Francis
Aims and background Omentin-1 (oment-1) is a type of adipokines that is mainly expressed
in visceral fat tissue. Based on accumulating evidence, oment-1 is closely related to …

[HTML][HTML] Bone marrow adipocytes and lung cancer bone metastasis: unraveling the role of adipokines in the tumor microenvironment

J Li, J Wu, Y Xie, X Yu - Frontiers in Oncology, 2024 - frontiersin.org
Bone is a common site of metastasis for lung cancer. The “seed and soil” hypothesis
suggests that the bone marrow microenvironment (“soil”) may provide a conducive survival …

Innate immune response in hypertension

JB De Sanctis - Current Pharmaceutical Design, 2022 - benthamdirect.com
Even though an association between inflammation and hypertension has been known for
many years, it has not been simple to ascertain the role of several physiological responses …