NETosis: molecular mechanisms, role in physiology and pathology

NV Vorobjeva, BV Chernyak - Biochemistry (Moscow), 2020 - Springer
NETosis is a program for formation of neutrophil extracellular traps (NETs), which consist of
modified chromatin decorated with bactericidal proteins from granules and cytoplasm …

Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome

JS Knight, Y Kanthi - Seminars in immunopathology, 2022 - Springer
Antiphospholipid syndrome (APS) is an autoimmune thrombophilia propelled by circulating
antiphospholipid antibodies that herald vascular thrombosis and obstetrical complications …

Neutrophils and NETs in modulating acute and chronic inflammation

FVS Castanheira, P Kubes - … Journal of the American Society of …, 2019 - ashpublications.org
Neutrophils are an absolutely essential part of the innate immune system, playing an
essential role in the control of infectious diseases but more recently are also being viewed …

Neutrophils in tissue injury and repair

J Wang - Cell and tissue research, 2018 - Springer
As one of the first defenders of innate immune response, neutrophils make a rapid and
robust response against infection or harmful agents. While traditionally regarded as suicidal …

Mechanism of development of atherosclerosis and cardiovascular disease in diabetes mellitus

N Katakami - Journal of atherosclerosis and thrombosis, 2018 - jstage.jst.go.jp
Diabetic macroangiopathy, atherosclerosis secondary to diabetes mellitus (DM), causes
cerebro-cardiovascular diseases, which are major causes of death in patients with DM and …

Neutrophil extracellular traps in the second decade

V Brinkmann - Journal of innate immunity, 2018 - karger.com
Nearly 15 years after the first description of neutrophil extracellular traps (NETs), our
knowledge concerning this structure has expanded considerably. Initially, NETs were …

E-cigarette use causes a unique innate immune response in the lung, involving increased neutrophilic activation and altered mucin secretion

B Reidel, G Radicioni, PW Clapp, AA Ford… - American journal of …, 2018 - atsjournals.org
Rationale: E-cigarettes have become increasingly popular and little is known about their
potential adverse health effects. Objectives: To determine the effects of e-cigarette use on …

HMGB1 in health and disease

R Kang, R Chen, Q Zhang, W Hou, S Wu, L Cao… - Molecular aspects of …, 2014 - Elsevier
Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

[HTML][HTML] Mitochondria as central hub of the immune system

CN de Souza Breda, GG Davanzo, PJ Basso… - Redox biology, 2019 - Elsevier
Nearly 130 years after the first insights into the existence of mitochondria, new
rolesassociated with these organelles continue to emerge. As essential hubs that dictate cell …

NETosis: how vital is it?

BG Yipp, P Kubes - Blood, The Journal of the American Society …, 2013 - ashpublications.org
In this review, we examine the evidence that neutrophil extracellular traps (NETs) play a
critical role in innate immunity. We summarize how NETs are formed in response to various …