A practical guide to evaluating colocalization in biological microscopy
KW Dunn, MM Kamocka… - American Journal of …, 2011 - journals.physiology.org
Fluorescence microscopy is one of the most powerful tools for elucidating the cellular
functions of proteins and other molecules. In many cases, the function of a molecule can be …
functions of proteins and other molecules. In many cases, the function of a molecule can be …
Cytoskeleton–membrane interactions in membrane raft structure
GR Chichili, W Rodgers - Cellular and molecular life sciences, 2009 - Springer
Cell membranes are structurally heterogeneous, composed of discrete domains with unique
physical and biological properties. Membrane domains can form through a number of …
physical and biological properties. Membrane domains can form through a number of …
Quantifying colocalization by correlation: the Pearson correlation coefficient is superior to the Mander's overlap coefficient
J Adler, I Parmryd - Cytometry Part A, 2010 - Wiley Online Library
The Pearson correlation coefficient (PCC) and the Mander's overlap coefficient (MOC) are
used to quantify the degree of colocalization between fluorophores. The MOC was …
used to quantify the degree of colocalization between fluorophores. The MOC was …
Interleaflet coupling, pinning, and leaflet asymmetry—major players in plasma membrane nanodomain formation
T Fujimoto, I Parmryd - Frontiers in cell and developmental biology, 2017 - frontiersin.org
The plasma membrane has a highly asymmetric distribution of lipids and contains dynamic
nanodomains many of which are liquid entities surrounded by a second, slightly different …
nanodomains many of which are liquid entities surrounded by a second, slightly different …
[HTML][HTML] Toward understanding the dynamics of membrane-raft-based molecular interactions
A Kusumi, K Suzuki - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2005 - Elsevier
The cell membrane is a 2-dimensional non-ideal liquid containing dynamic structures on
various time-space scales, and the raft domain is one of them. Existing literature supports …
various time-space scales, and the raft domain is one of them. Existing literature supports …
One lipid, multiple functions: how various pools of PI(4,5)P2 are created in the plasma membrane
K Kwiatkowska - Cellular and molecular life sciences, 2010 - Springer
Abstract Phosphatidylinositol 4, 5-bisphosphate [PI (4, 5) P 2] is a minor lipid of the inner
leaflet of the plasma membrane that controls the activity of numerous proteins and serves as …
leaflet of the plasma membrane that controls the activity of numerous proteins and serves as …
[HTML][HTML] Actin filaments attachment at the plasma membrane in live cells cause the formation of ordered lipid domains
J Dinic, P Ashrafzadeh, I Parmryd - Biochimica et Biophysica Acta (BBA) …, 2013 - Elsevier
The relationship between ordered plasma membrane nanodomains, known as lipid rafts,
and actin filaments is the focus of this study. Plasma membrane order was followed in live …
and actin filaments is the focus of this study. Plasma membrane order was followed in live …
Regulation and cellular roles of phosphoinositide 5-kinases
PAO Weernink, M Schmidt, KH Jakobs - European journal of pharmacology, 2004 - Elsevier
The membrane phospholipid, phosphatidylinositol 4, 5-bisphosphate (PIP2), plays a critical
role in various, apparently very different cellular processes. As precursor for second …
role in various, apparently very different cellular processes. As precursor for second …
The T cell receptor resides in ordered plasma membrane nanodomains that aggregate upon patching of the receptor
J Dinic, A Riehl, J Adler, I Parmryd - Scientific reports, 2015 - nature.com
Two related models for T cell signalling initiation suggest either that T cell receptor (TCR)
engagement leads to its recruitment to ordered membrane domains, often referred to as lipid …
engagement leads to its recruitment to ordered membrane domains, often referred to as lipid …
Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D
K Eleme, SB Taner, B Önfelt, LM Collinson… - The Journal of …, 2004 - rupress.org
Cell surface proteins major histocompatibility complex (MHC) class I–related chain A (MICA)
and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor …
and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor …