Despite tremendous efforts in the past two years, our understanding of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), virus–host interactions, immune …

We analyzed data from two ongoing COVID-19 longitudinal serological surveys in Orange
County, CA., between April 2020 and March 2021. A total of 8476 finger stick blood …

Immunodominant epitope discovery platforms play an important role in identifying novel
biomarkers for effective immunotherapies and diagnostics. Methods to analyze the B-cell …

Early in the SARS-CoV-2 pandemic, there was a high level of optimism based on
observational studies and small controlled trials that treating hospitalized patients with …

Novel high-throughput protein detection technologies are critically needed for population-
based large-scale SARS-CoV-2 antibody detection as well as for monitoring quality and …

Recent studies provide conflicting evidence on the persistence of SARS-CoV-2 immunity
induced by mRNA vaccines. Here, we aim to quantify the persistence of humoral immunity …

Background Early evaluations of healthcare professional (HCP) COVID-19 risk occurred
during insufficient personal protective equipment and disproportionate testing, contributing …

We analyzed data from two ongoing serologic surveys, a longitudinal cohort of health care
workers (HCW) from the University of California Irvine Medical Center (Orange County, CA …

Introduction The outbreak of the newly discovered human coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has disrupted the normal life of almost …

Vaccines trigger an immunological response that includes B and T cells, with B cells
producing antibodies. SARS-CoV-2 immunity weakens over time after vaccination …