The unifying hypothesis of Alzheimer's disease: Heparan sulfate proteoglycans/glycosaminoglycans are key as first hypothesized over 30 years ago
AD Snow, JA Cummings, T Lake - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
The updated “Unifying Hypothesis of Alzheimer's disease”(AD) is described that links all the
observed neuropathology in AD brain (ie, plaques, tangles, and cerebrovascular amyloid …
observed neuropathology in AD brain (ie, plaques, tangles, and cerebrovascular amyloid …
Phospho-tau and chromatin landscapes in early and late Alzheimer's disease
L Gil, SA Niño, C Guerrero… - International Journal of …, 2021 - mdpi.com
Cellular identity is determined through complex patterns of gene expression. Chromatin, the
dynamic structure containing genetic information, is regulated through epigenetic …
dynamic structure containing genetic information, is regulated through epigenetic …
Co-expression network analysis of human tau-transgenic mice reveals protein modules associated with tau-induced pathologies
K Tsumagari, Y Sato, A Shimozawa, H Aoyagi… - Iscience, 2022 - cell.com
Abnormally accumulated tau protein aggregates are one of the hallmarks of
neurodegenerative diseases, including Alzheimer's disease (AD). In order to investigate …
neurodegenerative diseases, including Alzheimer's disease (AD). In order to investigate …