Mind the gap: from neurons to networks to outcomes in multiple sclerosis

DT Chard, AAS Alahmadi, B Audoin… - Nature Reviews …, 2021 - nature.com
MRI studies have provided valuable insights into the structure and function of neural
networks, particularly in health and in classical neurodegenerative conditions such as …

Optical coherence tomography (OCT) in neuro-ophthalmology

N Minakaran, ER de Carvalho, A Petzold, SH Wong - Eye, 2021 - nature.com
Optical coherence tomography (OCT) is a non-invasive medical imaging technology that is
playing an increasing role in the routine assessment and management of patients with …

Dynamics of retinal injury after acute optic neuritis

I Gabilondo, EH Martínez‐Lapiscina… - Annals of …, 2015 - Wiley Online Library
Objective We set out to assess the dynamics of retinal injury after acute optic neuritis (ON)
and their association with clinical visual outcomes. Methods Thirty‐one consecutive patients …

Reliability of intra-retinal layer thickness estimates

T Oberwahrenbrock, M Weinhold, J Mikolajczak… - PloS one, 2015 - journals.plos.org
Purpose Measurement of intra-retinal layer thickness using optical coherence tomography
(OCT) has become increasingly prominent in multiple sclerosis (MS) research …

Lesions in the posterior visual pathway promote trans-synaptic degeneration of retinal ganglion cells

J Keller, BF Sánchez-Dalmau, P Villoslada - PLoS One, 2014 - journals.plos.org
Objective Retrograde trans-synaptic degeneration of retinal ganglion cell layer (GCL) has
been proposed as one of the mechanisms contributing to permanent disability after visual …

Retinal asymmetry in multiple sclerosis

A Petzold, SYL Chua, AP Khawaja, PA Keane… - Brain, 2021 - academic.oup.com
The diagnosis of multiple sclerosis is based on a combination of clinical and paraclinical
tests. The potential contribution of retinal optical coherence tomography (OCT) has been …

Modifications in macular perfusion and neuronal loss after acute traumatic brain injury

JL Hepschke, E Laws, NHB Saliman… - … & Visual Science, 2023 - iovs.arvojournals.org
Purpose: Traumatic brain injury (TBI) causes structural damage and functional impairment in
the visual system, often with retinal ganglion cell (RGC) degeneration occurring without …

[图书][B] Visual fields via the visual pathway

F Rowe - 2016 - books.google.com
This book is a basic reference guide on the anatomy of the visual pathway, the
layout/topography of the nerve fibers throughout the visual pathway, typical lesions affecting …

Patterns of retrograde axonal degeneration in the visual system

WA de Vries-Knoppert, JC Baaijen, A Petzold - Brain, 2019 - academic.oup.com
Conclusive evidence for existence of acquired retrograde axonal degeneration that is truly
trans-synaptic (RTD) has not yet been provided for the human visual system. Convincing …

Exploring experimental autoimmune optic neuritis using multimodal imaging

P Manogaran, C Walker-Egger, M Samardzija… - Neuroimage, 2018 - Elsevier
Background Neuro-axonal injury is a key contributor to non-reversible long-term disability in
multiple sclerosis (MS). However, the underlying mechanisms are not yet fully understood …