Obesity and its comorbidities, including type 2 diabetes mellitus, cardiovascular disease,
heart failure and non-alcoholic liver disease are a major health and economic burden with …

Obesity is one of the major challenges for public health in 21st century, with 1.9 billion
people being considered as overweight and 600 million as obese. There are certain …

Dietary protein enhances satiety and promotes weight loss, but the mechanisms by which
appetite is affected remain unclear. We investigated the role of gut hormones, key regulators …

The last decade has witnessed a marked increase in our understanding of the importance of
gut hormones in the regulation of energy homeostasis. In particular, the discovery that the …

The increasing prevalence of obesity worldwide has imparted renewed impetus to the study
of the mechanisms of appetite regulation. Digestion and nutrient absorption take place in the …

Obesity is one of the greatest public health challenges of the 21st century with 1.6 billion
adults currently classified as being overweight and 400 million as obese. Obesity is causally …

Gut hormones signal to the central nervous system to influence energy homeostasis.
Evidence supports the existence of a system in the gut that senses the presence of food in …

Objective: To quantify plasma concentrations of hormones that regulate energy homeostasis
in order to establish possible mechanisms for greater weight loss after Roux‐en‐Y gastric …

Bariatric surgery is the only effective treatment for patients with morbid obesity. This is no
solution to the present obesity pandemic however. Currently licensed non-surgical …

The gut hormone peptide YY (PYY) was recently proposed to comprise an endogenous
satiety factor. We have studied acute anorectic functions of PYY (3–36) in mice and rats, as …