Mitochondria are not only central organelles in metabolism and energy conversion but are
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …

Biogenesis of mitochondria requires the import of approximately 1,000 different precursor
proteins into and across the mitochondrial membranes. Mitochondria exhibit a wide variety …

Liver mitochondria undergo architectural remodeling that maintains energy homeostasis in
response to feeding and fasting. However, the specific components and molecular …

Mitochondria are essential organelles performing important cellular functions ranging from
bioenergetics and metabolism to apoptotic signaling and immune responses. They are …

Mitochondria perform crucial functions in cellular metabolism, protein and lipid biogenesis,
quality control, and signaling. The systematic analysis of protein complexes and interaction …

APOO/MIC26 is a subunit of the MICOS complex required for mitochondrial cristae
morphology and function. Here, we report a novel variant of the APOO/MIC26 gene that …

The mitochondrial inner membrane plays central roles in bioenergetics and metabolism and
contains several established membrane protein complexes. Here, we report the …

β‐barrel membrane proteins in the mitochondrial outer membrane are crucial for mediating
the metabolite exchange between the cytosol and the mitochondrial intermembrane space …

Mitochondrial cristae expand the surface area of respiratory membranes and ultimately
allow for the evolutionary scaling of respiration with cell volume across eukaryotes. The …

Mitochondrial cristae architecture is crucial for optimal respiratory function of the organelle.
Cristae shape is maintained in part by the mitochondrial contact site and cristae organizing …