There are 18 mammalian cytochrome P450 (CYP) families, which encode 57 genes in the
human genome. CYP2, CYP3 and CYP4 families contain far more genes than the other 15 …

Two concepts for the long-term regulation of arterial pressure were considered in this
review, the neural control hypothesis and the volume regulation hypothesis. The role of the …

These studies were designed to investigate sex differences in renal hemodynamics under
control conditions and in response to two different cyclooxygenase inhibitors. Studies were …

The protean properties of 20-hydroxyeicosatetraenoic acid (HETE), vasoactivity,
mitogenicity, and modulation of transport in key nephron segments, serve as the basis for …

The VASCULAR endothelium lining as a monolayer the entire circulatory system does not
represent a passive diffusion barrier but displays the features of a distributed organ (1 to 1.5 …

The cytochrome P-450 pathway of AA metabolism is widely distributed and gives rise to a
diversity of products affecting basic biological mechanisms such as vascular reactivity and …

Purified synthetic products from the cytochrome P450 pathway of arachidonate metabolism
were applied to the intestinal serosa. Arteriolar blood flow was calculated using video …

Previous studies from this and other laboratories have shown that angiotensin II (AII)
induces [Ca2+] i transients in proximal tubular epithelium independent of phospholipase C …

Arachidonic acid metabolism through the cytochrome P450-dependent monooxygenase
system has been the subject of considerable research interest over the last several years …

The role of endogenous arachidonic acid and its metabolites as mediators of cell growth
was studied in rat mesangial cells. Inhibitors of the cytochrome P450 monooxygenase and …