Cells interact with their surrounding environment through a combination of static and
dynamic mechanical signals that vary over stimulus types, intensity, space, and time …

Orthopedic implants are widely used for the treatment of bone defects caused by injury,
infection, tumor and congenital diseases. However, poor osseointegration and implant …

Topical instillation of cyclosporin A (an anti‐inflammatory drug) is clinically recommended as
the first‐line treatment for dry eye disease. Nevertheless, it suffers from poor ocular drug …

Cells sense and respond to a variety of physical cues from their surrounding
microenvironment, and these are interpreted through mechanotransductive processes to …

In this work, a simple method was proposed to produce dense composite polysaccharide-
based membranes to be used for guided tissue and guided bone regeneration. The …

Nanostructure provides a closer structural support approximation to native bone architecture
for cells and further regulates cell's behavior, resulting in the formation of functional tissues …

Bone presents an intrinsic ability for self-regeneration and repair, however critical defects
and large fractures require invasive and time-consuming clinical interventions. As an …

Hydrophilic and nanotextured surfaces for dental implants have been reported as relevant
properties for early osseointegration. However, these surface characteristics are quite …

Cellular microenvironments play a crucial role in cell behavior. In addition to the biochemical
cues present in the microenvironments, biophysical and biomechanical properties on …

Severe bone injuries can result in disabilities and thus affect a person's quality of life.
Mesenchymal stem cells (MSCs) can be an alternative for bone healing by growing them on …