[HTML][HTML] Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

JS Tregoning, KE Flight, SL Higham, Z Wang… - Nature reviews …, 2021 - nature.com
Where 2020 saw the development and testing of vaccines against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has …

[HTML][HTML] Phylogenetic and phylodynamic approaches to understanding and combating the early SARS-CoV-2 pandemic

SW Attwood, SC Hill, DM Aanensen… - Nature Reviews …, 2022 - nature.com
Determining the transmissibility, prevalence and patterns of movement of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections is central to our understanding …

[HTML][HTML] Antibody evasion by the P. 1 strain of SARS-CoV-2

W Dejnirattisai, D Zhou, P Supasa, C Liu, AJ Mentzer… - Cell, 2021 - cell.com
Terminating the SARS-CoV-2 pandemic relies upon pan-global vaccination. Current
vaccines elicit neutralizing antibody responses to the virus spike derived from early isolates …

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

MG Joyce, HAD King, I Elakhal-Naouar… - Science translational …, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
stresses the continued need for next-generation vaccines that confer broad protection …

SARS-CoV-2 viral variants—tackling a moving target

JR Mascola, BS Graham, AS Fauci - Jama, 2021 - jamanetwork.com
In this issue of JAMA, Zhang and colleagues1 report the emergence of a novel severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) variant in Southern California that …

[HTML][HTML] Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines

AC Walls, MC Miranda, A Schäfer, MN Pham… - Cell, 2021 - cell.com
Understanding vaccine-elicited protection against SARS-CoV-2 variants and other
sarbecoviruses is key for guiding public health policies. We show that a clinical stage …

[HTML][HTML] SARS-CoV-2 variants of concern

JY Choi, DM Smith - Yonsei medical journal, 2021 - ncbi.nlm.nih.gov
Since the COVID-19 pandemic first began in December 2019, the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) virus has continuously evolved with many variants …

[HTML][HTML] Antigenic cartography of well-characterized human sera shows SARS-CoV-2 neutralization differences based on infection and vaccination history

W Wang, S Lusvarghi, R Subramanian, NJ Epsi… - Cell host & …, 2022 - cell.com
The rapid emergence of SARS-CoV-2 variants challenges vaccination strategies. Here, we
collected 201 serum samples from persons with a single infection or multiple vaccine …

[HTML][HTML] The role of B cells in COVID-19 infection and vaccination

S Chen, F Guan, F Candotti, K Benlagha… - Frontiers in …, 2022 - frontiersin.org
B cells secrete antibodies and mediate the humoral immune response, making them
extremely important in protective immunity against SARS-CoV-2, which caused the …

[HTML][HTML] Molecular insights into receptor binding energetics and neutralization of SARS-CoV-2 variants

M Koehler, A Ray, RA Moreira, B Juniku… - Nature …, 2021 - nature.com
Despite an unprecedented global gain in knowledge since the emergence of SARS-CoV-2,
almost all mechanistic knowledge related to the molecular and cellular details of viral …