BODIPYs are photosensitizers activatable by light to generate highly reactive singlet oxygen
(1 O 2) from molecular oxygen, leading to tissue damage in the photoirradiated region …

This minireview is devoted to honoring the memory of Dr. Thomas Dougherty, a pioneer of
modern photodynamic therapy (PDT). It compiles the most important inputs made by our …

Nowadays, both cancer and infections caused by antibiotic resistant microorganisms are
problems that affect the entire planet. Phototherapy (namely photodynamic therapy (PDT) …

Over the past 30 years, photodynamic therapy (PDT) has shown great development. In the
clinical setting the few approved molecules belong almost exclusively to the porphyrin …

Photodynamic therapy (PDT) is a minimally invasive technique for the treatment of target
malignant tumors via the generation of highly reactive singlet oxygen species. PDT …

Immune system evasion by cancer cells is one of the hallmarks of cancers, and it occurs with
the support of tumor-associated immune cells (TICs) in the tumor microenvironment that …

Singlet oxygen (1O2) is the excited state of ground, triplet state, molecular oxygen (O2).
Photosensitized 1O2 has been extensively studied as one of the reactive oxygen species …

Simple Summary Photodynamic therapy (PDT) is a cancer treatment that uses
photogenerated reactive oxygen species (ROS) to damage target cells. The unique …

The most used approaches in structure-based drug design possess peculiar characteristics
with advantages and limitations, and thus the management of complementary data from …

Current anticancer drug discovery and development efforts are aimed at identifying new
complexes that can potently and selectively target DNA and modulate the functions of target …