Deep tissue two-photon microscopy

F Helmchen, W Denk - Nature methods, 2005 - nature.com
With few exceptions biological tissues strongly scatter light, making high-resolution deep
imaging impossible for traditional—including confocal—fluorescence microscopy. Nonlinear …

Nonlinear magic: multiphoton microscopy in the biosciences

WR Zipfel, RM Williams, WW Webb - Nature biotechnology, 2003 - nature.com
Multiphoton microscopy (MPM) has found a niche in the world of biological imaging as the
best noninvasive means of fluorescence microscopy in tissue explants and living animals …

A large field of view two-photon mesoscope with subcellular resolution for in vivo imaging

NJ Sofroniew, D Flickinger, J King, K Svoboda - elife, 2016 - elifesciences.org
Imaging is used to map activity across populations of neurons. Microscopes with cellular
resolution have small (< 1 millimeter) fields of view and cannot simultaneously image activity …

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

L Madisen, TA Zwingman, SM Sunkin, SW Oh… - Nature …, 2010 - nature.com
The Cre/lox system is widely used in mice to achieve cell-type-specific gene expression.
However, a strong and universally responding system to express genes under Cre control is …

[HTML][HTML] ScanImage: flexible software for operating laser scanning microscopes

TA Pologruto, BL Sabatini, K Svoboda - Biomedical engineering online, 2003 - Springer
Background Laser scanning microscopy is a powerful tool for analyzing the structure and
function of biological specimens. Although numerous commercial laser scanning …

[PDF][PDF] Principles of two-photon excitation microscopy and its applications to neuroscience

K Svoboda, R Yasuda - Neuron, 2006 - cell.com
The brain is complex and dynamic. The spatial scales of interest to the neurobiologist range
from individual synapses (∼ 1 μm) to neural circuits (centimeters); the timescales range from …

[图书][B] Introduction to nanoscience and nanotechnology

GL Hornyak, HF Tibbals, J Dutta, JJ Moore - 2008 - api.taylorfrancis.com
The maturation of nanotechnology has revealed it to be a unique and distinct discipline
rather than a specialization within a larger field. Its textbook cannot afford to be a chemistry …

Optical brain imaging in vivo: techniques<?xpp qa?> and applications from animal to man

EMC Hillman - Journal of biomedical optics, 2007 - spiedigitallibrary.org
Optical brain imaging has seen 30 years of intense development, and has grown into a rich
and diverse field. In-vivo imaging using light provides unprecedented sensitivity to functional …

[图书][B] Smart CMOS image sensors and applications

J Ohta - 2020 - taylorfrancis.com
Revised and expanded for this new edition, Smart CMOS Image Sensors and Applications,
Second Edition is the only book available devoted to smart CMOS image sensors and …

[HTML][HTML] Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion

CB Schaffer, B Friedman, N Nishimura… - PLoS …, 2006 - journals.plos.org
A highly interconnected network of arterioles overlies mammalian cortex to route blood to
the cortical mantle. Here we test if this angioarchitecture can ensure that the supply of blood …