On virus growth and form

R Zandi, B Dragnea, A Travesset, R Podgornik - Physics Reports, 2020 - Elsevier
We review approaches aimed at deciphering the physical mechanisms responsible for viral
structure and assembly. We discuss the basic principles of condensed matter physics …

Tailoring lumazine synthase assemblies for bionanotechnology

Y Azuma, TGW Edwardson, D Hilvert - Chemical Society Reviews, 2018 - pubs.rsc.org
Nanoscale compartments formed by hierarchical protein self-assembly are valuable
platforms for nanotechnology development. The well-defined structure and broad chemical …

Viral nanoparticles: Current advances in design and development

SS Arul, B Balakrishnan, SS Handanahal… - Biochimie, 2024 - Elsevier
Viral nanoparticles (VNPs) are self-assembling, adaptable delivery systems for vaccines and
other therapeutic agents used in a variety of biomedical applications. The potential of …

Multiscale modeling of hepatitis B virus capsid assembly and its dimorphism

F Mohajerani, B Tyukodi, CJ Schlicksup… - ACS …, 2022 - ACS Publications
Hepatitis B virus (HBV) is an endemic, chronic virus that leads to 800000 deaths per year.
Central to the HBV lifecycle, the viral core has a protein capsid assembled from many copies …

Peptide-directed encapsulation of inorganic nanoparticles into protein containers

M Künzle, J Mangler, M Lach, T Beck - Nanoscale, 2018 - pubs.rsc.org
Biomolecules can be combined with inorganic compounds to unite biological features with
the chemical and physical properties of abiotic materials. In particular, protein containers …

The equilibrium structure of self-assembled protein nano-cages

S Panahandeh, S Li, R Zandi - Nanoscale, 2018 - pubs.rsc.org
Understanding how highly symmetric, robust, monodisperse protein nano-cages self-
assemble can have major applications in various areas of bio-nanotechnology, such as drug …

Packaging of DNA origami in viral capsids

I Kopatz, R Zalk, Y Levi-Kalisman, E Zlotkin-Rivkin… - Nanoscale, 2019 - pubs.rsc.org
Here we show the encapsulation of 35 nm diameter, nearly-spherical, DNA origami by self-
assembly of SV40-like (simian virus 40) particles. The self-assembly of this new type of …

Mechanisms of scaffold-mediated microcompartment assembly and size control

F Mohajerani, E Sayer, C Neil, K Inlow, MF Hagan - ACS nano, 2021 - ACS Publications
This article describes a theoretical and computational study of the dynamical assembly of a
protein shell around a complex consisting of many cargo molecules and long, flexible …

The role of the encapsulated cargo in microcompartment assembly

F Mohajerani, MF Hagan - PLoS computational biology, 2018 - journals.plos.org
Bacterial microcompartments are large, roughly icosahedral shells that assemble around
enzymes and reactants involved in certain metabolic pathways in bacteria. Motivated by …

Cargo-compatible encapsulation in virus-based nanoparticles

L Li, C Xu, W Zhang, F Secundo, C Li, ZP Zhang… - Nano Letters, 2019 - ACS Publications
Molecule encapsulation in virus-based nanoparticles (VNPs) is an emerging bioinspired
way to design novel functional nanostructures and devices. Here, we report a general cargo …