How can immunopathology shape the evolution of parasite virulence?

GH Long, M Boots - Trends in Parasitology, 2011 - cell.com
Immunopathology (immune-mediated pathology) is a ubiquitous cause of disease during
infection, but how will parasite exploitation strategies evolve in its presence …

Assessing the risk of vaccine-driven virulence evolution in SARS-CoV-2

IF Miller, CJE Metcalf - Royal Society Open Science, 2022 - royalsocietypublishing.org
The evolution of SARS-CoV-2 virulence, or lethality, threatens to exacerbate the burden of
COVID-19 on society. How might COVID-19 vaccines alter selection for increased SARS …

Evolution of virulence in heterogeneous host communities under multiple trade-offs

EE Osnas, AP Dobson - Evolution, 2012 - academic.oup.com
Many pathogens and parasites are transmitted through hosts that differ in species, sex,
genotype, or immune status. In addition, virulence (here defined as disease-induced …

Integrating infection intensity into within-and between-host pathogen dynamics: Implications for invasion and virulence evolution

MQ Wilber, F Pfab, ME Ohmer… - The American …, 2021 - journals.uchicago.edu
Infection intensity can dictate disease outcomes but is typically ignored when modeling
infection dynamics of microparasites (eg, bacteria, virus, and fungi). However, for a number …

The evolution of post-infection mortality

CM Saad-Roy, A White, M Boots - Proceedings B, 2024 - royalsocietypublishing.org
COVID-19 infections have underlined that there can be substantial impacts on health after
recovery, including elevated mortality. While such post-infection mortality (PIM) is clearly …

Within-host dynamics of mycoplasma infections: Conjunctivitis in wild passerine birds

PJ Hurtado - Journal of Theoretical Biology, 2012 - Elsevier
The host–pathogen interaction drives infectious disease dynamics at the individual,
population and community levels. Here I present and analyze a model of the vertebrate …

Body size and meta-community structure: the allometric scaling of parasitic worm communities in their mammalian hosts

GA De Leo, AP Dobson, M Gatto - Parasitology, 2016 - cambridge.org
In this paper we derive from first principles the expected body sizes of the parasite
communities that can coexist in a mammal of given body size. We use a mixture of …

The influence of host demography, pathogen virulence, and relationships with pathogen virulence on the evolution of pathogen transmission in a spatial context

SM Messinger, A Ostling - Evolutionary Ecology, 2013 - Springer
A major challenge in evolutionary ecology is to explain extensive natural variation in
transmission rates and virulence across pathogens. Host and pathogen ecology is a …

Complex interactions in the life cycle of a simple parasite shape the evolution of virulence

LM Silva, JC Koella - bioRxiv, 2024 - biorxiv.org
Evolutionary expectations about the virulence of parasites (ie, the parasite-induced mortality
rate of the host) generally describe parasites which grow and are transmitted at the same …

[图书][B] Paleoepidemiology of Mesopotamia and the ancient Near East: The impact of zoonotic diseases and population demographics on infectious disease patterns

JS Rashidi - 2011 - search.proquest.com
This study reconstructs the paleoepidemiology of zoonoses and other infectious diseases in
Mesopotamia and the ancient Near East from the Early Bronze Age through the Late Iron …