The development of novel synthetic strategies to form new chemical entities in a
stereoselective manner is an ongoing significant objective in organic and medicinal …

Structurally diverse pyridinium salts are quite familiar structures in many natural products
and bioactive pharmaceuticals. Over the centuries, these privileged scaffolds have played …

An efficient solvent free method is developed for the preparation of structurally diverse 1-
alkoxymethylphosphonium chlorides in high yield. One of the prepared salts derived from (1 …

Medicinal plants are well-known in affording clinically useful agents, with rich medicinal
values by combining with disease targets through various mechanisms. Plant secondary …

Corynantheine-type alkaloids are major components of the Mitragyna speciosa, also known
as kratom, that exhibit unique pharmacological activity. However, no universal method to …

In recent years, environmental and economic reasons have motivated the development of
transition metal‐free carbon‐carbon bond forming reactions and some excellent reviews …

Two separate commercial products of kratom [Mitragyna speciosa (Korth.) Havil. Rubiaceae]
were used to generate reference standards of its indole and oxindole alkaloids. While …

Divergent cascade syntheses constitute a highly attractive and challenging area in synthetic
chemistry, and can exhibit unexpected chemoselectivity. Herein, a Brønsted acid-controlled …

N-Fused 5/7-membered bicycles have witnessed apparent importance in many bioactive
molecules, but there are rare examples to construct these privileged scaffolds by asymmetric …

Hydrazides, NN containing structural motifs, are important due to their presence in a wide
variety of biologically significant compounds. While the homo NN coupling of two NH …