Resistance to cancer therapy remains a major challenge in clinical oncology. Although the
initial treatment phase is often successful, eventual resistance, characterized by tumour …

Breast cancer is the most frequently diagnosed cancer and the principal cause of mortality
by malignancy in women and represents a main problem for public health worldwide. Tumor …

Inorganic mercury, though a key component of pediatric vaccines, is an environmental
toxicant threatening human health via accumulating oxidative stress in part. Luteolin has …

Abstract The Cancer Genome Atlas (TCGA) has unveiled genomic deregulation of various
components of the extrinsic and intrinsic apoptotic pathways in different types of cancers …

Immune checkpoint inhibitors (ICIs) have transformed the treatment paradigm for several
malignancies. While the use of single-agent or combined ICIs has achieved acceptable …

A fascinating but uncharacterized action of antimitotic chemotherapy is to collectively prime
cancer cells to apoptotic mitochondrial outer membrane permeabilization (MOMP), while …

Resistance to chemotherapy still remains a major challenge in the clinic, impairing the
quality of life and survival rate of patients. The identification of unconventional …

The aim of the study was to investigated the mechanism of Strychnos nux-vomica L.(Semen
Strychni, SS) against papillary carcinoma thyroid (PTC) by combined of network …

Tumor necrosis factor superfamily (TNFSF) resistance contributes to the development and
progression of tumors and resistance to various cancer therapies. Tumor-intrinsic alterations …

Microtubules are multifunctional cytoskeletal proteins that are involved in crucial cellular
roles including maintenance of cell shape, intracellular transport, meiosis, and mitosis. Class …