Models of cochlea used in Cochlear implant research: a review

F Hrncirik, I Roberts, I Sevgili, C Swords… - Annals of Biomedical …, 2023 - Springer
As the first clinically translated machine-neural interface, cochlear implants (CI) have
demonstrated much success in providing hearing to those with severe to profound hearing …

In-vitro study of speed and alignment angle in cochlear implant electrode array insertions

P Aebischer, G Mantokoudis, S Weder… - IEEE transactions on …, 2021 - ieeexplore.ieee.org
Objective: The insertion of the electrode array is a critical step in cochlear implantation.
Herein we comprehensively investigate the impact of the alignment angle and feed-forward …

Impact of scala tympani geometry on insertion forces during implantation

F Hrncirik, IV Roberts, C Swords, PJ Christopher… - Biosensors, 2022 - mdpi.com
(1) Background: During a cochlear implant insertion, the mechanical trauma can cause
residual hearing loss in up to half of implantations. The forces on the cochlea during the …

Human cochlear microstructures at risk of electrode insertion trauma, elucidated in 3D with contrast-enhanced microCT

A Starovoyt, G Pyka, T Putzeys, T Balcaen… - Scientific Reports, 2023 - nature.com
Cochlear implant restores hearing loss through electrical stimulation of the hearing nerve
from within the cochlea. Unfortunately, surgical implantation of this neuroprosthesis often …

Methods for multiscale structural and functional analysis of the mammalian cochlea

C Vogl, J Neef, C Wichmann - Molecular and Cellular Neuroscience, 2022 - Elsevier
The mammalian cochlea is a snail-shaped structure deeply that is embedded in the
temporal bone and harbors the auditory sensory epithelium–the organ of Corti. Since the …

Variations in microanatomy of the human modiolus require individualized cochlear implantation

M Pietsch, D Schurzig, R Salcher, A Warnecke… - Scientific Reports, 2022 - nature.com
Cochlear variability is of key importance for the clinical use of cochlear implants, the most
successful neuroprosthetic device that is surgically placed into the cochlear scala tympani …

Determination of the round window niche anatomy using cone beam computed tomography imaging as preparatory work for individualized drug-releasing implants

F Matin, Z Gao, F Repp, S John, T Lenarz, V Scheper - Journal of Imaging, 2021 - mdpi.com
Modern therapy of inner ear disorders is increasingly shifting to local drug delivery using a
growing number of pharmaceuticals. Access to the inner ear is usually made via the round …

Precise evaluation of the postoperative cochlear duct length by flat-panel volume computed tomography–Application of secondary reconstructions

P Schendzielorz, L Ilgen, FT Müller-Graff… - Cochlear Implants …, 2022 - Taylor & Francis
Objective There is still a lack in precise postoperative evaluation of the cochlea because of
strong artifacts. This study aimed to improve accuracy of postoperative two-turn (2TL) and …

Development and in-silico and ex-vivo validation of a software for a semi-automated segmentation of the round window niche to design a patient specific implant to …

F Matin-Mann, Z Gao, C Wei, F Repp, EN Artukarslan… - Journal of …, 2023 - mdpi.com
The aim of this study was to develop and validate a semi-automated segmentation approach
that identifies the round window niche (RWN) and round window membrane (RWM) for use …

Incomplete Partition Type II Cochlear Malformations: Delineating the Three-Dimensional Structure from Digitized Human Histopathological Specimens

C Swords, A Geerardyn, MY Zhu, JT O'Malley… - Otology & …, 2023 - journals.lww.com
Background IP-II is a commonly implanted cochlear malformation. Detailed knowledge of
intracochlear three-dimensional (3D) morphology may assist with cochlear implant (CI) …