Dietary and metabolic therapies have been attempted in a wide variety of neurological
diseases, including epilepsy, headache, neurotrauma, Alzheimer disease, Parkinson …

Choline is an essential nutrient for humans. It is a precursor of membrane phospholipids (eg,
phosphatidylcholine (PC)), the neurotransmitter acetylcholine, and via betaine, the methyl …

Diverse brain insults, including traumatic brain injury, stroke, infections, tumors,
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …

Understanding molecular mechanisms mediating epileptogenesis is critical for developing
more effective therapies for epilepsy. We recently found that the mammalian target of …

Epilepsy is a group of chronic neurological disorders characterized by recurrent,
spontaneous, and unpredictable seizures. It is one of the most common neurological …

ObjectiveEpilepsy is a chronic neurological disease characterised with seizures. The
aetiology of the most generalised epilepsies cannot be explicitly determined and the …

Posttraumatic epilepsy (PTE) is a prevalent type of acquired epilepsy secondary to traumatic
brain injury, and is characterized by repeated seizures. Traditional antiepileptic drugs have …

Epilepsy is one of the oldest neurological conditions known to humankind. It is known that
oxidative stress and generation of reactive oxygen species are a cause and consequence of …

Epilepsy is a neurological disorder characterized by the presence of seizures and
neuropsychiatric comorbidities. Despite the number of antiepileptic drugs, one-third of …

Glial glutamate transporter EAAT2 plays a major role in glutamate clearance in synaptic
clefts. Several lines of evidence indicate that strategies designed to increase EAAT2 …