Cobalt is an essential metal that is found in very low abundance in the body and the
environment. Cobalt coordination complexes exhibit interesting redox and magnetic …

Purpose Hydroxocobalamin, or vitamin B12 (V-B12), is frequently used to treat smoke
inhalation and cyanide poisoning. Recent reports have also described its use to treat …

Many of nitric oxide's biological effects are mediated via NO binding to the iron in heme-
containing proteins. Cobalamin (vitamin B 12) is structurally similar to heme and is a cofactor …

Background/Aim: Cancer cells have an essential demand for vitamin B12 (cobalamin) to
enable cellular replication. The present pilot study quantified the immunohistochemical …

A photoactive manganese nitrosyl, namely [Mn (PaPy3)(NO)](ClO4)({Mn-NO}), has been
loaded into the columnar pores of an MCM-41 host. Strong interaction between the polar …

The intrinsic factor (IF) vitamin B12 ileum anchored receptor, cubilin, mediates endocytotic
uptake of the IF complex of vitamin B12 to the blood serum. This receptor was targeted for …

We have previously demonstrated that nitrosylcobalamin (NO-Cbl), an analogue of vitamin B
12 that delivers nitric oxide (NO), had potent antiproliferative activity against several human …

We have previously demonstrated the anti-tumor activity of nitrosylcobalamin (NO-Cbl), an
analog of vitamin B12 that delivers nitric oxide (NO) and increases the expression of tumor …

Numerous reports in recent literature claim that NO binds to aquacobalamine (vitamin B12a)
to produce a nitrosyl complex, and that this reaction plays an important role in various …

In humans, cobalamin or vitamin B 12 is delivered to two target enzymes via a complex
intracellular trafficking pathway comprising transporters and chaperones. CblC (or …