What is holding back the development of antiviral metallodrugs? A literature overview and implications for SARS-CoV-2 therapeutics and future viral outbreaks

REF de Paiva, AM Neto, IA Santos, ACG Jardim… - Dalton …, 2020 - pubs.rsc.org
In light of the Covid-19 outbreak, this review brings together historical and current literature
efforts towards the development of antiviral metallodrugs. Classical compounds such as …

Design, classification, and adverse effects of NSAIDs: A review on recent advancements

M Arfeen, A Srivastava, N Srivastava, RA Khan… - Bioorganic & Medicinal …, 2024 - Elsevier
Inflammation is a hallmark of many diseases, including cancer, neurodegenerative diseases
like Alzheimer's, type II diabetes, rheumatoid arthritis, and asthma. Nonsteroidal anti …

Plausible PEPPSI catalysts for direct C–H functionalization of five-membered heterocyclic bioactive motifs: synthesis, spectral, X-ray crystallographic characterizations …

D Bensalah, L Mansour, M Sauthier, N Gurbuz… - RSC …, 2023 - pubs.rsc.org
In this study, a series of benzimidazolium salts were synthesized as asymmetric N-
heterocyclic carbene (NHC) precursors. Nine novel palladium complexes with the general …

Palladium (II) complexes of substituted salicylaldehydes: Synthesis, characterization and investigation of their biological profile

A Zianna, G Geromichalos, AM Fiotaki… - Pharmaceuticals, 2022 - mdpi.com
Five palladium (II) complexes of substituted salicylaldehydes (X-saloH, X= 4-Et2N (for 1), 3,
5-diBr (for 2), 3, 5-diCl (for 3), 5-F (for 4) or 4-OMe (for 5)) bearing the general formula [Pd (X …

Silver (I) and gold (I) complexes with sulfasalazine: Spectroscopic characterization, theoretical studies and antiproliferative activities over Gram-positive and Gram …

AT Fiori-Duarte, REF de Paiva, CM Manzano… - Journal of Molecular …, 2020 - Elsevier
The emergence of bacterial strains resistant to antibiotics, such as the sulfonamides (sulfa
drugs), is currently a case of concern. The synthesis of metal complexes using well-known …

Synthesis, structure and biological activity of silver (I) complexes containing triphenylphosphine and non-steroidal anti-inflammatory drug ligands

FJ Ma, X Huang, XY Li, SL Tang, DJ Li… - Journal of Inorganic …, 2024 - Elsevier
Two Ag (I) complexes containing triphenylphosphine and non-steroidal anti-inflammatory
drug ligands were synthesized and investigated using various spectroscopic studies and …

[HTML][HTML] Computational analysis of substituent effect on indole derivatives as potential antibacterial agents

S Bince, SS Dindorkar, A Yadav - Chemical Physics Impact, 2022 - Elsevier
In recent years, indole derivatives have gained attention as an important class of
antimicrobial drugs. The modification of 1, 3, 4-oxadiazole and 1, 2, 4-triazole, which are …

Spectroscopic and Microscopic Analyses of Fe3O4/Au Nanoparticles Obtained by Laser Ablation in Water

M Muniz-Miranda, F Muniz-Miranda, E Giorgetti - Nanomaterials, 2020 - mdpi.com
Magneto-plasmonic nanoparticles constituted of gold and iron oxide were obtained in an
aqueous environment by laser ablation of iron and gold targets in two successive steps …

Cytotoxic activity of nitrogen, sulfur, and oxygen chelated Pt (II) complexes; their DNA/BSA binding by in vitro and in silico approaches

R Bhaduri, S Mandal, SK Tarai, A Pan… - Journal of Molecular …, 2022 - Elsevier
A series of Pt (II) complexes [Pt (PEA) Cl 2], Pt1;[Pt (PEA)(OH 2) 2](NO 3) 2, Pt2;[Pt
(PEA)(LC)]+ Pt3;[Pt (PEA)(NAC)] Pt4;[Pt (PEA)(CBDCA)] Pt5, and [Pt (PEA)(ox)] Pt6 with …

Photophysical, photodynamical, redox properties and BSA interactions of novel isomeric tetracationic peripheral palladium (ii)-bipyridyl porphyrins

F da Silveira Santos, CH da Silveira, FS Nunes… - Dalton …, 2020 - pubs.rsc.org
New isomeric tetra-cationic porphyrins containing peripheral [Pd (bpy) Cl]+ units attached to
pyridyl substituents were synthesized and fully characterized. The porphyrins present an …