The role of polyphenol (flavonoids) compounds in the treatment of cancer cells

A Hazafa, KU Rehman, N Jahan, Z Jabeen - Nutrition and cancer, 2020 - Taylor & Francis
Cancer remains a second leading cause of deaths and major public health problem. It
occurs due to extensive DNA damage caused by ultraviolet radiations, ionizing radiations …

[HTML][HTML] Flavones: from biosynthesis to health benefits

N Jiang, AI Doseff, E Grotewold - Plants, 2016 - mdpi.com
Flavones correspond to a flavonoid subgroup that is widely distributed in the plants, and
which can be synthesized by different pathways, depending on whether they contain C-or O …

[HTML][HTML] Therapeutic role of flavonoids and flavones in cancer prevention: Current trends and future perspectives

AU Khan, HS Dagur, M Khan, N Malik, M Alam… - European Journal of …, 2021 - Elsevier
Cancer is one of notorious diseases across the globe. Therapeutic approaches for cancer
are often expensive and develop severe side effects, and usually result comorbidities …

Plant flavonoids in cancer chemoprevention: role in genome stability

VC George, G Dellaire, HPV Rupasinghe - The Journal of nutritional …, 2017 - Elsevier
Carcinogenesis is a multistage process that involves a series of events comprising of
genetic and epigenetic changes leading to the initiation, promotion and progression of …

Apigenin: A current review on its beneficial biological activities

X Zhou, F Wang, R Zhou, X Song… - Journal of Food …, 2017 - Wiley Online Library
Abstract Apigenin, identified as 4′, 5, 7‐trihydroxyflavone, is a natural flavonoid compound
present in a variety of fruits, vegetables, functional foods, and medicinal plants. Many studies …

[HTML][HTML] Flavonoids: New frontier for immuno-regulation and breast cancer control

M Sudhakaran, S Sardesai, AI Doseff - Antioxidants, 2019 - mdpi.com
Breast cancer (BC) remains the second most common cause of cancer-related deaths in
women in the US, despite advances in detection and treatment. In addition, breast cancer …

[HTML][HTML] Role of induced programmed cell death in the chemopreventive potential of apigenin

JY Jang, B Sung, ND Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
The flavonoid apigenin (4′, 5, 7-trihydroxyflavone), which is one of the most widely
distributed phytochemicals in the plant kingdom, is one of the most thoroughly investigated …

Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes

GS Temba, V Kullaya, T Pecht, BT Mmbaga… - Nature …, 2021 - nature.com
Abstract Sub-Saharan Africa currently experiences an unprecedented wave of urbanization,
which has important consequences for health and disease patterns. This study aimed to …

Molecular basis for the action of a dietary flavonoid revealed by the comprehensive identification of apigenin human targets

D Arango, K Morohashi, A Yilmaz… - Proceedings of the …, 2013 - National Acad Sciences
Flavonoids constitute the largest class of dietary phytochemicals, adding essential health
value to our diet, and are emerging as key nutraceuticals. Cellular targets for dietary …

[HTML][HTML] Bioprospecting Dodonaea viscosa Jacq.; a traditional medicinal plant for antioxidant, cytotoxic, antidiabetic and antimicrobial potential

MN Malik, I Haq, H Fatima, M Ahmad, I Naz… - Arabian Journal of …, 2022 - Elsevier
Purpose of study Dodonaea viscosa Jacq. is an ethnomedicinal plant that has been
extensively used for the treatment of gout, rheumatism and pain. Current study was …