Background The TP53 gene, encoding tumour suppressor protein p53, is located on the
short arm of chromosome 17 (17p). Patients with 17p deletion (del17p) chronic lymphocytic …

Despite the introduction of many novel therapies into the clinic to target hematological
malignancies, glucocorticoids (GCs) still remain one of the cornerstone drugs in first-line …

The article provides information on diagnosis and management of chronic lymphocytic
leukemia (CLL). It informs about diagnosis of the CLL which includes lymphocyte …

In recent years there has been significant progress in the treatment of chronic lymphocytic
leukemia, first due to the introduction of immunochemotherapy with monoclonal antibodies …

Despite the combinations of chemotherapy with monoclonal antibodies have further
improved response rates, chronic lymphocytic leukemia (CLL) remains an incurable disease …

Chronic lymphocytic leukaemia (CLL) is an indolent B‐cell malignancy with heterogeneous
outcomes. Chromosomal abnormalities in CLL are predictive of the natural disease course; …

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia and it typically
afflicts older adults, with a median age at diagnosis of 71. Traditional treatments for CLL …

Introduction: The last decade has witnesd immense progress in the treatment of chronic
lymphocytic leukemia (CLL). Chemoimmunotherapy (CIT) combining rituximab and …

Introduction: Management of refractory chronic lymphocytic leukemia (CLL) represents a
major challenge because of the poor prognosis and limited treatment options. While …

BACKGROUND: High-dose methylprednisolone is active in treatment of relapsed/refractory
chronic lymphocytic leukemia (CLL) but infectious toxicity is serious. The aim of this project …