Inflammation in obesity, diabetes, and related disorders

TV Rohm, DT Meier, JM Olefsky, MY Donath - Immunity, 2022 - cell.com
Obesity leads to chronic, systemic inflammation and can lead to insulin resistance (IR), β-cell
dysfunction, and ultimately type 2 diabetes (T2D). This chronic inflammatory state …

Skeletal muscle inflammation and insulin resistance in obesity

H Wu, CM Ballantyne - The Journal of clinical investigation, 2017 - Am Soc Clin Investig
Obesity is associated with chronic inflammation, which contributes to insulin resistance and
type 2 diabetes mellitus. Under normal conditions, skeletal muscle is responsible for the …

Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?

K Rehman, MSH Akash - Journal of biomedical science, 2016 - Springer
Background Insulin resistance (IR) is one of the major hallmark for pathogenesis and
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …

Lipid signaling and lipotoxicity in metaflammation: indications for metabolic disease pathogenesis and treatment

ME Ertunc, GS Hotamisligil - Journal of lipid research, 2016 - ASBMB
Lipids encompass a wide variety of molecules such as fatty acids, sterols, phospholipids,
and triglycerides. These molecules represent a highly efficient energy resource and can act …

Disuse-induced skeletal muscle atrophy in disease and nondisease states in humans: mechanisms, prevention, and recovery strategies

EA Nunes, T Stokes, J McKendry… - … of Physiology-Cell …, 2022 - journals.physiology.org
Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …

Metabolic endotoxemia with obesity: Is it real and is it relevant?

NE Boutagy, RP McMillan, MI Frisard, MW Hulver - Biochimie, 2016 - Elsevier
Obesity is associated with metabolic derangements in multiple tissues, which contribute to
the progression of insulin resistance and the metabolic syndrome. The underlying stimulus …

[HTML][HTML] Testosterone: a metabolic hormone in health and disease

DM Kelly, TH Jones - Journal of Endocrinology, 2013 - joe.bioscientifica.com
Testosterone is a hormone that plays a key role in carbohydrate, fat and protein metabolism.
It has been known for some time that testosterone has a major influence on body fat …

Oxidative stress and metabolic syndrome

CK Roberts, KK Sindhu - Life sciences, 2009 - Elsevier
Metabolic syndrome is a collection of cardiometabolic risk factors that includes obesity,
insulin resistance, hypertension and dyslipidemia. Although there has been significant …

[图书][B] OZONE.

V Bocci - 2011 - Springer
Is there any reason to write a third book on the topic of oxygen-ozone therapy? The first was
written four years ago for italian physicians, who, for some time, had complained about the …

aaUrgent Needs of Caregiving in Ageing Populations with Alzheimer's Disease and Other Chronic Conditions: Support Our Loved Ones

JW Culberson, J Kopel, U Sehar, PH Reddy - Ageing Research Reviews, 2023 - Elsevier
The ageing process begins at birth. It is a life-long process, and its exact origins are still
unknown. Several hypotheses attempt to describe the normal ageing process, including …