Strecker reaction and α-amino nitriles: Recent advances in their chemistry, synthesis, and biological properties

VV Kouznetsov, CEP Galvis - Tetrahedron, 2018 - Elsevier
Abstract α-Amino nitrile compounds have a profound impact on bio-chemical sciences, as
they have been prepared from inexpensive starting materials and have become valuable …

Synthetic approaches to the new drugs approved during 2017

AC Flick, CA Leverett, HX Ding, E McInturff… - Journal of Medicinal …, 2019 - ACS Publications
New drugs introduced to the market every year represent privileged structures for particular
biological targets. These new chemical entities (NCEs) provide insight into molecular …

The inhibitive performance of 2, 3-pyrazine dicarboxylic acid and synergistic impact of KI during acid corrosion of 70/30 and 90/10 copper–nickel alloys

IC Ukaga, PC Okafor, IB Onyeachu, AI Ikeuba… - Materials Chemistry and …, 2023 - Elsevier
Pyrazine derivatives are efficient environmentally–safe chemicals for protecting metallic
materials against corrosion during industrial acid cleaning. However, they have been mostly …

Pyrazine derivatives as green oil field corrosion inhibitors for steel

IB Obot, SA Umoren, NK Ankah - Journal of Molecular Liquids, 2019 - Elsevier
The inhibitive efficacy of environmental friendly pyrazine derivatives, 2, 3-pyrazine
dicarboxylic acid (Pyrazine C), pyrazine carboxamide (Pyrazine E) and 2-methoxy-3-(1 …

Urea Hydrogen Peroxide and Ethyl Lactate, an Eco-Friendly Combo System in the Direct C(sp2)–H Bond Selenylation of Imidazo[2,1-b]thiazole and Related …

CAO Moraes, RBC Santos, MFO Cavalcante… - Acs Omega, 2023 - ACS Publications
Herein, we describe a urea hydrogen peroxide-mediated sustainable protocol for the
synthesis of selenylated imidazo [2, 1-b] thiazole by using half molar equivalent diorganyl …

Imidazo [1, 2-a] pyridines: Promising drug candidate for antitumor therapy

R Goel, V Luxami, K Paul - Current Topics in Medicinal …, 2016 - ingentaconnect.com
Imidazo [1, 2-a] pyridine has been shown to be an important biologically active moiety. This
review is a compilation of the scattered output of results of the anticancer activities of the …

Solvent–solute interactions, electronic properties, topological and biological explorations of 6-Bromo-7-methylimidazo [1, 2-a] pyridine

S Selvakumari, A Irfan, S Muthu - Journal of Molecular Liquids, 2023 - Elsevier
Abstract Theoretical studies of 6-Bromo-7-methylimidazo [1, 2-a] pyridine employing density
functional theory has been accomplished in this present work. The caption compound's …

Novel and Selective TLR7 Antagonists among the Imidazo[1,2-a]pyrazines, Imidazo[1,5-a]quinoxalines, and Pyrazolo[1,5-a]quinoxalines Series

N Bou Karroum, G Moarbess, JF Guichou… - Journal of Medicinal …, 2019 - ACS Publications
The Toll-like receptors (TLRs) 7 and 8 play an important role in the immune system
activation, and their agonists may therefore serve as promising candidate vaccine adjuvants …

Novel iron doped calcium oxalates as promising heterogeneous catalysts for one-pot multi-component synthesis of pyranopyrazoles

KK Gangu, S Maddila, SN Maddila… - RSC advances, 2017 - pubs.rsc.org
The co-precipitation method using a surface modifier, glutamic acid was employed in the
design of iron doped calcium oxalates (Fe-CaOx). Fe-CaOx with diverse iron loading (0.5 …

Efficient Access to Imidazo[1,2-a]pyridines/pyrazines/pyrimidines via Catalyst-Free Annulation Reaction under Microwave Irradiation in Green Solvent

RN Rao, B Mm, B Maiti, R Thakuria… - ACS Combinatorial …, 2018 - ACS Publications
An expeditious catalyst-free heteroannulation reaction for imidazo [1, 2-a]
pyridines/pyrimidines/pyrazines was developed in green solvent under microwave …