[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy

BH Kok, HT Lim, CP Lim, NS Lai, CY Leow, CH Leow - Virus research, 2023 - Elsevier
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …

New insights into the immunopathology and control of dengue virus infection

G Screaton, J Mongkolsapaya, S Yacoub… - Nature Reviews …, 2015 - nature.com
Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …

[HTML][HTML] Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico

DF Robbiani, L Bozzacco, JR Keeffe, R Khouri… - Cell, 2017 - cell.com
Antibodies to Zika virus (ZIKV) can be protective. To examine the antibody response in
individuals who develop high titers of anti-ZIKV antibodies, we screened cohorts in Brazil …

Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond

V Boldescu, MAM Behnam, N Vasilakis… - Nature Reviews Drug …, 2017 - nature.com
Infections with flaviviruses, such as dengue, West Nile virus and the recently re-emerging
Zika virus, are an increasing and probably lasting global risk. This Review summarizes and …

Receptors and routes of dengue virus entry into the host cells

C Cruz-Oliveira, JM Freire… - FEMS microbiology …, 2015 - academic.oup.com
Dengue is the most prevalent arthropod-borne viral disease, caused by dengue virus, a
member of the Flaviviridae family. Its worldwide incidence is now a major health problem …

Dengue infection

MG Guzman, DJ Gubler, A Izquierdo… - Nature reviews Disease …, 2016 - nature.com
Dengue is widespread throughout the tropics and local spatial variation in dengue virus
transmission is strongly influenced by rainfall, temperature, urbanization and distribution of …

Broadly neutralizing antiviral antibodies

D Corti, A Lanzavecchia - Annual review of immunology, 2013 - annualreviews.org
A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive
immune response. The widely held view has been that the great variability of viral …

A structural perspective of the flavivirus life cycle

S Mukhopadhyay, RJ Kuhn… - Nature Reviews …, 2005 - nature.com
Abstract Dengue, Japanese encephalitis, West Nile and yellow fever belong to the Flavivirus
genus, which is a member of the Flaviviridae family. They are human pathogens that cause …

Cryo-EM structure of the mature dengue virus at 3.5-Å resolution

X Zhang, P Ge, X Yu, JM Brannan, G Bi… - Nature structural & …, 2013 - nature.com
Regulated by pH, membrane-anchored proteins E and M function during dengue virus
maturation and membrane fusion. Our atomic model of the whole virion from cryo–electron …

Dengue virus life cycle: viral and host factors modulating infectivity

IA Rodenhuis-Zybert, J Wilschut, JM Smit - Cellular and molecular life …, 2010 - Springer
Abstract Dengue virus (DENV 1-4) represents a major emerging arthropod-borne pathogen.
All four DENV serotypes are prevalent in the (sub) tropical regions of the world and infect 50 …