Fear and the defense cascade: clinical implications and management
K Kozlowska, P Walker, L McLean… - Harvard review of …, 2015 - journals.lww.com
Evolution has endowed all humans with a continuum of innate, hard-wired, automatically
activated defense behaviors, termed the defense cascade. Arousal is the first step in …
activated defense behaviors, termed the defense cascade. Arousal is the first step in …
Behavioral arrest: in search of the neural control system
WR Klemm - Progress in Neurobiology, 2001 - Elsevier
Scientists have spent hundreds of years trying to understand how the brain controls
movement. Why has there been so little interest in knowing how the brain STOPS …
movement. Why has there been so little interest in knowing how the brain STOPS …
Localization of mu-opioid receptors on amygdaloid projection neurons in the parabrachial nucleus of the rat
The parabrachial nucleus (PB) is a major relay of noxious and non-noxious visceral sensory
information from the nucleus of the solitary tract, spinal cord, and spinal trigeminal nucleus to …
information from the nucleus of the solitary tract, spinal cord, and spinal trigeminal nucleus to …
Cannabidiol has a unique effect on global brain activity: a pharmacological, functional MRI study in awake mice
AH Sadaka, AG Ozuna, RJ Ortiz, P Kulkarni… - Journal of Translational …, 2021 - Springer
Background The phytocannabinoid cannabidiol (CBD) exhibits anxiolytic activity and has
been promoted as a potential treatment for post-traumatic stress disorders. How does CBD …
been promoted as a potential treatment for post-traumatic stress disorders. How does CBD …
Pharmacological and biochemical aspects of GABAergic neurotransmission: pathological and neuropsychobiological relationships
RO Beleboni, ROG Carolino, AB Pizzo… - Cellular and molecular …, 2004 - Springer
The GABAergic neurotransmission has been implicated in the modulation of many neural
networks in forebrain, midbrain and hindbrain, as well as, in several neurological disorders …
networks in forebrain, midbrain and hindbrain, as well as, in several neurological disorders …
Serotonergic neural links from the dorsal raphe nucleus modulate defensive behaviours organised by the dorsomedial hypothalamus and the elaboration of fear …
Decrease of γ-aminobutyric acid (GABA)-mediated neurotransmission in the dorsomedial
hypothalamus (DMH) evokes instinctive fear-like responses. The aim of the present study …
hypothalamus (DMH) evokes instinctive fear-like responses. The aim of the present study …
Supraspinal connections and termination patterns of the parabrachial complex determined by the biocytin anterograde tract-tracing technique in the rat
R BIANCHI, G Corsetti, L RODELLA… - The Journal of …, 1998 - cambridge.org
We have re-evaluated, using the anterograde tracer biocytin, supraspinal efferent
projections from the parabrachial complex (PBN) to gain new information about the nature of …
projections from the parabrachial complex (PBN) to gain new information about the nature of …
Neuroanatomical and neuropharmacological study of opioid pathways in the mesencephalic tectum: effect of μ1-and κ-opioid receptor blockade on escape behavior …
MY Osaki, L Castellan-Baldan, F Calvo, AD Carvalho… - Brain research, 2003 - Elsevier
Deep layers of the superior colliculus (DLSC), the dorsal and ventral periaqueductal gray
matter (PAG), and inferior colliculus (IC) are midbrain structures involved in the generation of …
matter (PAG), and inferior colliculus (IC) are midbrain structures involved in the generation of …
Cingulate nociceptive circuitry and roles in pain processing: the cingulate premotor pain model
BA Vogt, RW Sikes - Cingulate neurobiology and disease, 2009 - books.google.com
A long tradition conceptualizes pain processing according to sensory-discriminative and
affective-motivational domains (Melzack & Casey, 1968; Melzack, 1975; Kenshalo & Willis …
affective-motivational domains (Melzack & Casey, 1968; Melzack, 1975; Kenshalo & Willis …
Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the …
B Lobão-Soares, R Walz, RDS Prediger… - Behavioural brain …, 2008 - Elsevier
The cellular prion protein (PrPC) is a neuronal anchored glycoprotein that has been
associated with distinct functions in the CNS, such as cellular adhesion and differentiation …
associated with distinct functions in the CNS, such as cellular adhesion and differentiation …