An updated review of folate-functionalized nanocarriers: A promising ligand in cancer

P Ebrahimnejad, AS Taleghani, K Asare-Addo… - Drug discovery today, 2022 - Elsevier
The uncontrolled release of drugs in conventional drug delivery systems has led to the
introduction of new nanotechnology-based drug delivery systems and the use of targeted …

Targeting nanoparticles to malignant tumors

N Sharma, K Bietar, U Stochaj - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
Nanomaterials are at the forefront of health research and development. Among different
nanomaterials, nanoparticles are especially promising for cancer theranostics. However …

tLyp–1: A peptide suitable to target NRP–1 receptor

L Larue, B Kenzhebayeva, MG Al-Thiabat… - Bioorganic …, 2023 - Elsevier
Targeting vascular endothelial growth factor receptor (VEFGR) and its co–receptor
neuropilin–1 (NRP–1) is an interesting vascular strategy. tLyp–1 is a tumor–homing and …

Potential Serotonin 5-HT2A Receptor Agonist of Psychoactive Components of Silene undulata Aiton: LC-MS/MS, ADMET, and Molecular Docking Studies

MB Alhawarri, S Olimat - Current Pharmaceutical Biotechnology, 2025 - benthamdirect.com
Background Silene undulata is historically used for inducing vivid and prophetic lucid
dreams, but limited information exists on its phytochemical composition and potential …

Exploring the Anticancer Potential of Furanpydone A: A Computational Study on its Inhibition of MTHFD2 Across Diverse Cancer Cell Lines

MB Alhawarri - Cell Biochemistry and Biophysics, 2024 - Springer
Cancer poses a significant global health challenge due to its high mortality rate and complex
treatment strategies. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), which is …

[HTML][HTML] Computational Insight of Oleracone L, Portulacatone B, and Portulacatal from Portulaca oleracea L. as Potential Anticholinesterase Inhibitors for Alzheimer's

SO Alshammari - Processes, 2024 - mdpi.com
Alzheimer's disease, characterized by a decline in cognitive functions, is frequently
associated with decreased levels of acetylcholine due to the overactivity of …

Synthesis, characterization and bioactivity of new pyridine-2(H)-one, nicotinonitrile, and furo[2,3-b]pyridine derivatives

MM Ibrahim, MN Azmi, MB Alhawarri, NNSNM Kamal… - Molecular Diversity, 2024 - Springer
Pyridone heterocycles, such as furo [2, 3-b] pyridines, have emerged as prominent scaffolds
in medicinal chemistry due to their versatile pharmacological properties, including significant …

Conjugated β-cyclodextrin enhances the affinity of folic acid towards FRα: molecular dynamics study

MG Al-Thiabat, AM Gazzali, N Mohtar, V Murugaiyah… - Molecules, 2021 - mdpi.com
Drug targeting is a progressive area of research with folate receptor alpha (FRα) receiving
significant attention as a biological marker in cancer drug delivery. The binding affinity of …

Novel Bis-thiazoles with pyridine and 1, 4-Dihydropyridine linkers as potential anti-Alzheimer agents

MA Said, SM Riyadh, NS Al-Kaff, MEA Zaki… - Journal of Molecular …, 2025 - Elsevier
A series of bis-hydrazonothiazoles with pyridine and 1, 4-dihydropyridine linkers was
synthesized using 2, 2′-[(2, 6-dimethyl-1, 4-dihydropyridine-3, 5-diyl) bis (ethan-1-yl-1 …

Naturally Occurring 8ß,13ß-kaur-15-en-17-al and Anti-Malarial Activity from Podocarpus polystachyus Leaves

MS Amir Rawa, MG Al-Thiabat, T Nogawa, Y Futamura… - Pharmaceuticals, 2022 - mdpi.com
Despite much interest and studies toward the genus Podocarpus, the anti-malarial
evaluation of Podocarpus polystachyus's phytoconstituents remains lacking. Herein, the …