Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease.

N Olvera, J Sánchez-Valle… - American Journal of …, 2024 - search.ebscohost.com
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition.
Objectives: We hypothesized that the unbiased integration of different COPD lung omics …

Optimizing miRNA transfection for screening in precision cut lung slices

J Nowakowska, N Gvazava… - … of Physiology-Lung …, 2024 - journals.physiology.org
Precision cut lung slices (PCLS) are complex three-dimensional (3-D) lung tissue models,
which preserve the native microenvironment, including cell diversity and cell-matrix …

Genetic variations in the antioxidant genes and their role in modulating susceptibility towards chronic obstructive pulmonary disease in the North Indian population

H Kansal, V Chopra, K Garg, S Sharma - Free Radical Biology and …, 2024 - Elsevier
Abstract Background Chronic Obstructive Pulmonary Disease (COPD) is a persistent
inflammatory lung condition characterized by an obstruction in removing oxygen from the …