Nanocrystals of poorly soluble drugs: drug bioavailability and physicochemical stability
Many approaches have been developed over time to overcome the bioavailability limitations
of poorly soluble drugs. With the advances in nanotechnology in recent decades, science …
of poorly soluble drugs. With the advances in nanotechnology in recent decades, science …
Drug nanocrystals in the commercial pharmaceutical development process
JP Möschwitzer - International journal of pharmaceutics, 2013 - Elsevier
Nanosizing is one of the most important drug delivery platform approaches for the
commercial development of poorly soluble drug molecules. The research efforts of many …
commercial development of poorly soluble drug molecules. The research efforts of many …
Nanotechnology based approaches for enhancing oral bioavailability of poorly water soluble antihypertensive drugs
Oral administration is the most convenient route among various routes of drug delivery as it
offers high patient compliance. However, the poor aqueous solubility and poor …
offers high patient compliance. However, the poor aqueous solubility and poor …
Drug nanocrystals–versatile option for formulation of poorly soluble materials
L Peltonen, J Hirvonen - International journal of pharmaceutics, 2018 - Elsevier
Poor solubility of drug compounds is a great issue in drug industry today and decreasing
particle size is one efficient and simple way to overcome this challenge. Drug nanocrystals …
particle size is one efficient and simple way to overcome this challenge. Drug nanocrystals …
Oral bioavailability: issues and solutions via nanoformulations
K Pathak, S Raghuvanshi - Clinical pharmacokinetics, 2015 - Springer
The delivery of drugs through the oral route is regarded as most optimal to achieve desired
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …
therapeutic effects and patient compliance. However, poor pharmacokinetic profiles of oral …
[HTML][HTML] Production and isolation of pharmaceutical drug nanoparticles
Nanosizing of pharmaceutical drug particles is one of the most important drug delivery
platforms approaches for the commercial development of poorly water-soluble drug …
platforms approaches for the commercial development of poorly water-soluble drug …
Nanosizing of drugs: effect on dissolution rate
The solubility, bioavailability and dissolution rate of drugs are important parameters for
achieving in vivo efficiency. The bioavailability of orally administered drugs depends on their …
achieving in vivo efficiency. The bioavailability of orally administered drugs depends on their …
Formation of nanosuspensions in bottom-up approach: theories and optimization
A Ahmadi Tehrani, MM Omranpoor, A Vatanara… - DARU Journal of …, 2019 - Springer
Background Nanosuspensions, liquid dispersions with nanometer size distribution, are
becoming trendy in pharmaceutical practice to formulate poorly water-soluble drugs and to …
becoming trendy in pharmaceutical practice to formulate poorly water-soluble drugs and to …
A brief literature and patent review of nanosuspensions to a final drug product
WWL Chin, J Parmentier, M Widzinski, EH Tan… - Journal of …, 2014 - Elsevier
Particle size reduction can be used for enhancing the dissolution of poorly water-soluble
drugs in order to enhance bioavailability. In nanosuspensions, the particle size of the drug is …
drugs in order to enhance bioavailability. In nanosuspensions, the particle size of the drug is …
[HTML][HTML] Drug nanocrystals: A way toward scale-up
KMR Srivalli, B Mishra - Saudi Pharmaceutical Journal, 2016 - Elsevier
Drug nanocrystals comprise unique drug delivery platforms playing a significantly important
and distinctive role in drug delivery and as such, the industry and academia are spending a …
and distinctive role in drug delivery and as such, the industry and academia are spending a …