[HTML][HTML] Microbial resistance movements: an overview of global public health threats posed by antimicrobial resistance, and how best to counter

S Dhingra, NAA Rahman, E Peile, M Rahman… - Frontiers in Public …, 2020 - frontiersin.org
Antibiotics changed medical practice by significantly decreasing the morbidity and mortality
associated with bacterial infection. However, infectious diseases remain the leading cause …

Evolution of drug resistance in Mycobacterium tuberculosis: a review on the molecular determinants of resistance and implications for personalized care

N Dookie, S Rambaran, N Padayatchi… - Journal of …, 2018 - academic.oup.com
Abstract Drug-resistant TB (DR-TB) remains a significant challenge in TB treatment and
control programmes worldwide. Advances in sequencing technology have significantly …

A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics

CRyPTIC Consortium - PLoS biology, 2022 - journals.plos.org
The Comprehensive Resistance Prediction for Tuberculosis: an International Consortium
(CRyPTIC) presents here a data compendium of 12,289 Mycobacterium tuberculosis global …

Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into the emergence and spread of multidrug resistance

AL Manson, KA Cohen, T Abeel, CA Desjardins… - Nature …, 2017 - nature.com
Multidrug-resistant tuberculosis (MDR-TB), caused by drug-resistant strains of
Mycobacterium tuberculosis, is an increasingly serious problem worldwide. Here we …

Factors predictive of the success of tuberculosis treatment: A systematic review with meta-analysis

NM Chaves Torres, JJ Quijano Rodríguez… - PloS one, 2019 - journals.plos.org
Objective To produce pooled estimates of the global results of tuberculosis (TB) treatment
and analyze the predictive factors of successful TB treatment. Methods Studies published …

Drug-resistant tuberculosis: a persistent global health concern

M Farhat, H Cox, M Ghanem, CM Denkinger… - Nature Reviews …, 2024 - nature.com
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …

Isoniazid-resistant tuberculosis: a cause for concern?

HR Stagg, MC Lipman, TD McHugh… - … International Journal of …, 2017 - ingentaconnect.com
The drug isoniazid (INH) is a key component of global tuberculosis (TB) control
programmes. It is estimated, however, that 16.1% of TB disease cases in the former Soviet …

First and second-line anti-tuberculosis drug-resistance patterns in pulmonary tuberculosis patients in Zambia

N Monde, M Munyeme, G Chongwe, JJ Wensman… - Antibiotics, 2023 - mdpi.com
Background: Drug-resistant tuberculosis has continued to be a serious global health threat
defined by complexity as well as higher morbidity and mortality wherever it occurs, Zambia …

Low-Level Rifampin Resistance and rpoB Mutations in Mycobacterium tuberculosis: an Analysis of Whole-Genome Sequencing and Drug Susceptibility Test Data in …

J Shea, TA Halse, D Kohlerschmidt… - Journal of clinical …, 2021 - Am Soc Microbiol
Rapid and reliable detection of rifampin (RIF) resistance is critical for the diagnosis and
treatment of drug-resistant and multidrug-resistant (MDR) tuberculosis. Discordant RIF …

Rifampicin mono-resistant tuberculosis—a review of an uncommon but growing challenge for global tuberculosis control

JH Malenfant, TF Brewer - Open forum infectious diseases, 2021 - academic.oup.com
Tuberculosis (TB) remains the leading cause of death by an infectious pathogen worldwide,
and drug-resistant TB is a critical and rising obstacle to global control efforts. Most scientific …