GABA-containing interneurons are crucial to both the development and function of the
cerebral cortex. Unlike cortical projection neurons, which have a relatively conserved set of …

Obsessive–compulsive disorder (OCD) is classified as an anxiety disorder in the DSM-IV-TR
[American Psychiatric Association, 2000. Diagnostic and statistical manual of mental …

In this report, which is an update of a guideline published in 2002 (Bandelow et al. 2002,
World J Biol Psychiatry 3: 171), recommendations for the pharmacological treatment of …

Childhood anxiety disorders represent one of the most common psychological disorders
found among the general population. They can be serious, distressful, and functionally …

Abstract Changes in serotonin neurotransmission have also been implicated in the etiology
and treatment of impulse control disorders, depression, and anxiety. We have investigated …

Rationale. A deregulation in concentrations of the neurosteroids (allo) pregnanolone and
3α, 5α-tetrahydrodeoxycorticosterone (3α, 5α-TH DOC) has been found in depressed …

Objectives: Brain imaging studies carried out in patients suffering from generalized anxiety
disorder (GAD) have contributed to better characterize the pathophysiological mechanisms …

Emphasis has been placed on understanding the mental health disparities that exist within
minority populations in the United States. Disparities are of particular importance when …

The most prevalent mental disorders, anxiety and mood disorders, are associated with both
functional and morphological brain changes that commonly involve the 'fear …

Abstract Study Objectives: To assess the effects of pregabalin compared with alprazolam
and placebo on aspects of sleep in healthy volunteers. Design: Randomized, double-blind …