Although psychoactive drugs have their therapeutic values, they have been implicated in the
pathogenesis of male infertility. This study highlights psychoactive drugs reported to impair …

The increasing use of opioid medications has become a crisis in developed countries. The
profound negative effects of opioids on male reproduction are well known, but this topic is …

Background: Opioids have been implicated to induce infertility. Although codeine remains
the most used opioid for recreational purpose, no study has documented its effect on sperm …

Background: Thymoquinone as the main active component of Nigella sativa might have a
various pharmacological effects such as antiapoptotic and antioxidant. Morphine is …

The developing brain is extremely sensitive to drugs during adolescence. The devastating
impacts of opioid abuse in this critical period not only do involve individuals but also are …

Recreational drug intake may be associated with a range of medical untoward
consequences, including male infertility. However, as the related evidence is still limited, the …

This paper is the fortieth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

Background The aim of the present study was to investigate the protective properties of
melatonin (MT) against oxidative stress, mitochondrial dysfunction, and apoptosis induced …

Pregabalin (PGB) drug abuse is common among the youth. It substituted tramadol before its
recent schedule as a controlled drug since April 2019. PGB is an antiepileptic drug acting on …

Background Chronic use of morphine is associated with reproductive complications, such as
hypogonadism and infertility. While the side effects of morphine have been extensively …