Methods for constructing and evaluating consensus genomic interval sets

J Rymuza, Y Sun, G Zheng, NJ LeRoy… - Nucleic Acids …, 2024 - academic.oup.com
The amount of genomic region data continues to increase. Integrating across diverse
genomic region sets requires consensus regions, which enable comparing regions across …

[PDF][PDF] Methods for evaluating unsupervised vector representations of genomic regions

G Zheng, J Rymuza, E Gharavi… - NAR Genomics and …, 2024 - academic.oup.com
Abstract Representation learning models have become a mainstay of modern genomics.
These models are trained to yield vector representations, or embeddings, of various …

Fast clustering and cell-type annotation of scATAC data using pre-trained embeddings

NJ LeRoy, JP Smith, G Zheng, J Rymuza… - NAR Genomics and …, 2024 - academic.oup.com
Data from the single-cell assay for transposase-accessible chromatin using sequencing
(scATAC-seq) are now widely available. One major computational challenge is dealing with …