Lipid metabolism, in particular the synthesis of fatty acids (FAs), is an essential cellular
process that converts nutrients into metabolic intermediates for membrane biosynthesis …

Immune cell trafficking is a critical element of the intestinal immune response, both in
homeostasis and in pathological conditions associated with inflammatory bowel disease …

Stroke is a leading cause of disability and mortality, with limited treatment options. After
stroke injury, microglia and CNS‐resident macrophages are rapidly activated and regulate …

Lysophospholipids are bioactive lipids and can signal through G-protein-coupled receptors
(GPCRs). The best studied lysophospholipids are lysophosphatidic acid (LPA) and …

Abstract Sphingosine-1-phosphate (S1P) is an important bioactive lipid molecule in cell
membrane metabolism and binds to G protein-coupled S1P receptors (S1PRs) to regulate …

Angiogenesis, the growth of new blood vessels, is a natural defense mechanism helping to
restore oxygen and nutrient supply to the affected brain tissue following an ischemic stroke …

Germinal matrix hemorrhage (GMH) is a devastating neurodevelopmental condition
affecting preterm infants, but why blood vessels in this brain region are vulnerable to rupture …

Abstract Sphingosine‐1‐phosphate (S1P) is a signalling lipid that regulates many cellular
processes in mammals. One well‐studied role of S1P signalling is to modulate T‐cell …

Lysophospholipids (LPs), including lysophosphatidic acid (LPA), sphingosine 1-phospate
(S1P), lysophosphatidylinositol (LPI), and lysophosphatidylserine (LysoPS), are bioactive …

Berberine is one of the most important quinoline alkaloids, which has shown numerous
pharmacological activities. There are pieces of evidence that berberine serves as a …