Background Piperine is a type of amide alkaloid that exhibits pleiotropic properties like
antioxidant, anticancer, anti-inflammatory, antihypertensive, hepatoprotective …

As the major naturally occurring alkaloid in pepper with a pungent taste, piperine is known
for its beneficial biological functions and therapeutic effects. In this work, the bioavailability …

Leading neurodegenerative diseases Alzheimer's disease (AD) and Parkinson's disease
(PD) are characterized by the impairment of memory and motor functions, respectively …

Depression is a major neuropsychiatric disease that considerably impacts individuals'
psychosocial function and life quality. Neurotrophic factors are now connected to the …

The neuroprotective properties of piperine, the major alkaloid extracted from black pepper,
have been under investigation, but its mechanism of action in excitotoxicity is still poorly …

Ethnopharmacological relevance Cross-cultural comparison of plants used during lactation
and the postpartum period offers insight into a largely overlooked area of …

Parkinson's disease (PD) is the most common progressive neurodegenerative disease
known to impart bradykinesia leading to diverse metabolic complications. Currently, scarcity …

Huntington's disease (HD) is an incorrigible neuropsychiatric disorder with reduced
cognition and motor abnormalities. Piperine (PIP) is an alkaloid with antioxidant, anti …

Piperine (PIP) has been known for its pharmacological activities with low water solubility and
poor dissolution, which limits its nutritional application. The purpose of this research was to …

Peppers have been used in clinics for a long time and its major component, piperine (PPR),
has been proven to be effective in the treatment of seizures. The purpose of this study was to …