FIV vaccine development and its importance to veterinary and human medicine: a review: FIV vaccine 2002 update and review

EW Uhl, TG Heaton-Jones, R Pu… - Veterinary immunology and …, 2002 - Elsevier
Feline immunodeficiency virus (FIV) is a natural infection of domestic cats that results in
acquired immunodeficiency syndrome resembling human immunodeficiency virus (HIV) …

FIV as a model for HIV: an overview

EE Sparger - In vivo models of HIV disease and control, 2006 - Springer
Animal models for human immunodeficiency virus (HIV) infection play a key role in
understanding the pathogenesis of AIDS and the development of therapeutic agents and …

Vaccine protection against feline immunodeficiency virus: setting the challenge

MJ Hosie, JA Beatty - Australian veterinary journal, 2007 - Wiley Online Library
Since feline immunodeficiency virus (FIV) was first isolated, international research efforts
have been directed towards developing a protective vaccine, not least because it may …

Vaccination against the feline immunodeficiency virus: the road not taken

S Lecollinet, J Richardson - Comparative immunology, microbiology and …, 2008 - Elsevier
Natural infection of domestic cats by the feline immunodeficiency virus (FIV) causes
acquired immunodeficiency syndrome (AIDS). FIV is genetically related to human …

Protective immunity against feline immunodeficiency virus induced by inoculation with vif-deleted proviral DNA

KM Lockridge, M Chien, GA Dean, KS Cole… - Virology, 2000 - Elsevier
To determine whether live-attenuated feline immunodeficiency virus (FIV) proviral DNA will
induce protective immunity, a plasmid clone constructed with a FIV provirus containing a …

AIDS vaccination studies using an ex vivo feline immunodeficiency virus model: failure to protect and possible enhancement of challenge infection by four cell-based …

S Giannecchini, P Isola, O Sichi, D Matteucci… - Journal of …, 2002 - Am Soc Microbiol
Immunogenicity and protective activity of four cell-based feline immunodeficiency virus (FIV)
vaccines prepared with autologous lymphoblasts were investigated. One vaccine was …

Evaluation of antibody parameters as potential correlates of protection or enhancement by experimental vaccines to equine infectious anemia virus

SA Hammond, ML Raabe, CJ Issel, RC Montelaro - Virology, 1999 - Elsevier
We previously demonstrated in trials of a variety of experimental vaccines to equine
infectious anemia virus (EIAV) a remarkable spectrum of efficacy ranging from sterilizing …

Tumor necrosis factor-α and virus expression in the central nervous system of cats infected with feline immunodeficiency virus

A Poli, M Pistello, MA Carli, F Abramo… - Journal of …, 1999 - Taylor & Francis
Cytokine disregulation has been implicated in the pathogenesis of lentivirus-induced
diseases. In the present study, 18 specific pathogen free (SPF) cats were inoculated with …

Targeted lymph node immunization can protect cats from a mucosal challenge with feline immunodeficiency virus

S Finerty, CR Stokes, TJ Gruffydd-Jones, TJ Hillman… - Vaccine, 2001 - Elsevier
With the rapid spread of human immunodeficiency virus (HIV) infection worldwide it is clear
that effective strategies for mucosal vaccination against lentiviruses are urgently required …

During readaptation in vivo, a tissue culture-adapted strain of feline immunodeficiency virus reverts to broad neutralization resistance at different times in individual …

M Bendinelli, M Pistello, D Del Mauro… - Journal of …, 2001 - Am Soc Microbiol
The broad resistance to antibody-mediated neutralization of lentiviruses recently isolated
from infected hosts is a poorly understood feature which might contribute to the ability of …