Cell transplantation for spinal cord injury: a systematic review

J Li, G Lepski - BioMed research international, 2013 - Wiley Online Library
Cell transplantation, as a therapeutic intervention for spinal cord injury (SCI), has been
extensively studied by researchers in recent years. A number of different kinds of stem cells …

Spinal cord regeneration

W Young - Cell transplantation, 2014 - journals.sagepub.com
Three theories of regeneration dominate neuroscience today, all purporting to explain why
the adult central nervous system (CNS) cannot regenerate. One theory proposes that Nogo …

Human bone marrow-derived and umbilical cord-derived mesenchymal stem cells for alleviating neuropathic pain in a spinal cord injury model

M Yousefifard, F Nasirinezhad… - Stem cell research & …, 2016 - Springer
Background Stem cell therapy can be used for alleviating the neuropathic pain induced by
spinal cord injuries (SCIs). However, survival and differentiation of stem cells following their …

Olfactory ensheathing cell transplantation after a complete spinal cord transection mediates neuroprotective and immunomodulatory mechanisms to facilitate …

RR Khankan, KG Griffis… - Journal of …, 2016 - Soc Neuroscience
Multiple neural and peripheral cell types rapidly respond to tissue damage after spinal cord
injury to form a structurally and chemically inhibitory scar that limits axon regeneration …

Understanding the neural repair-promoting properties of olfactory ensheathing cells

KCD Roet, J Verhaagen - Experimental neurology, 2014 - Elsevier
Olfactory ensheathing glial cells (OECs) are a specialized type of glia that form a
continuously aligned cellular pathway that actively supports unprecedented regeneration of …

Olfactory ensheathing cell transplantation in experimental spinal cord injury: effect size and reporting bias of 62 experimental treatments: a systematic review and meta …

R Watzlawick, J Rind, ES Sena, B Brommer… - PLoS …, 2016 - journals.plos.org
Olfactory ensheathing cell (OEC) transplantation is a candidate cellular treatment approach
for human spinal cord injury (SCI) due to their unique regenerative potential and autologous …

Survival and integration of transplanted olfactory ensheathing cells are crucial for spinal cord injury repair: insights from the last 10 years of animal model studies

R Reshamwala, M Shah, J St John… - Cell …, 2019 - journals.sagepub.com
Olfactory ensheathing cells (OECs), the glial cells of the primary olfactory nervous system,
support the natural regeneration of the olfactory nerve that occurs throughout life. OECs thus …

Biological roles of olfactory ensheathing cells in facilitating neural regeneration: a systematic review

H Yang, BR He, DJ Hao - Molecular neurobiology, 2015 - Springer
Continuous renewal of neurons throughout life in the olfactory system is often thought to be
partially attributable to specialized glial cells called olfactory ensheathing cells (OECs) …

Cell therapy augments functional recovery subsequent to spinal cord injury under experimental conditions

V Sabapathy, G Tharion, S Kumar - Stem Cells International, 2015 - Wiley Online Library
The spinal cord injury leads to enervation of normal tissue homeostasis ultimately leading to
paralysis. Until now there is no proper cure for the treatment of spinal cord injury. Recently …

The migration of olfactory ensheathing cells during development and regeneration

JAK Ekberg, D Amaya, A Mackay-Sim, JA St. John - Neurosignals, 2012 - karger.com
The primary olfactory nervous system is unique in that it continuously renews itself and
regenerates after injury. These properties are attributed to the presence of olfactory glia …