The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG
lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating …

The CA3 region of the hippocampus is important for rapid encoding of memory.
Computational theories have proposed specific roles in hippocampal function and memory …

Parallel recording of neuronal activity in the behaving animal is a prerequisite for our
understanding of neuronal representation and storage of information. Here we describe the …

Within the framework of a special issue on CA3, it was deemed relevant to summarize what
is known about the extrinsic and intrinsic wiring of CA3 as a basis for other contributions …

Activation of glycogen synthase kinase-3 (GSK-3) can cause memory deficits as seen in
Alzheimer's disease, the most common age-associated dementia, but the mechanism is not …

For many years part of the limbic system, the hippocampus, has been associated with
memory. The discovery of cooperativity in the nerve fibres of this part of the brain, where …

The hippocampus integrates the encoding, storage and recall of memories, binding the
spatio-temporal and sensory information that constitutes experience and keeping episodes …

Many theories of hippocampal function assume that area CA3 of hippocampus is capable of
performing rapid pattern storage, as well as pattern completion when a partial version of a …

Over the past four decades, a “standard framework” has emerged to explain the neural
mechanisms of episodic memory storage. This framework has been instrumental in driving …

Medial perforant path plasticity can be attenuated by 2-amino-5-phosphonovaleric acid
(APV) infusions, whereas lateral perforant path plasticity can be attenuated by naloxone …