High mortality rates have been reported after major amputations of a lower limb secondary
to diabetes and peripheral vascular disease. However, the mortality rates have varied …

• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Guideline Summary Chronic limb-threatening ischemia (CLTI) is associated with mortality,
amputation, and impaired quality of life. These Global Vascular Guidelines (GVG) are …

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BACKGROUND Diabetes mellitus causes a large majority of non-traumatic major and minor
amputations globally. Patients with diabetes are clinically complex with a multifactorial …

Introduction Major lower limb amputation is a significant event with substantial implications
for patients' quality of life. Care, treatment, and rehabilitation are largely governed by …

Background and purpose—For want of national guidelines for lower limb amputation (LLA)
the quality registry SwedeAmp was started in 2011 to increase knowledge around LLA and …

This study aimed to review epidemiology of diabetic foot (DF) amputation and provide a
pooled estimation of DF amputation rate in the region. A comprehensive search was …

Background Patients who undergo lower extremity amputation secondary to the
complications of diabetes or peripheral artery disease have poor long-term survival …

Background Historically, mortality rates after major lower limb amputations (LLAs) have
been very high. However, there are inconsistencies regarding the risk factors. The …