Human beings are adept at discerning relevant information from complex systems by
processing visual information. Similarly, as scientists labor to understand the fundamental …

The blood–brain barrier (BBB) is a dynamic and complex interface between blood and the
central nervous system that strictly controls the exchanges between the blood and brain …

A mass spectrometer is described as the smallest weighing scale ever used in the world. 1
Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which …

As a means to understand human neuropsychiatric disorders from human brain samples, we
compared the transcription patterns and histological features of postmortem brain to fresh …

Previously, we found decreased mitochondrial complex I subunits levels and increased
protein oxidation and nitration in postmortem prefrontal cortex (PFC) from patients with …

Brain banks are facilities providing an interface between generous donation of nervous
tissues and research laboratories devoted to increase our understanding of the diseases of …

After tissue or body fluid sampling, proteases and other protein-modifying enzymes can
rapidly change composition of the proteome. As a direct consequence, analytical results will …

Parkinson's disease (PD) pathology spreads throughout the brain following a region‐
specific process predominantly affecting the substantia nigra (SN) pars compacta. SN …

During the last decades, considerable advances in the understanding of specific
mechanisms underlying neurodegeneration in Parkinson's disease have been achieved, yet …

Brain banks are used to gather, store, and provide human brain tissue for research and have
been fundamental to improving our knowledge of the brain in health and disease. To …