Advances in drug delivery systems: Work in progress still needed?

F Laffleur, V Keckeis - International journal of pharmaceutics, 2020 - Elsevier
A new era of science and technology has emerged in pharmaceutical research with focus on
developing novel drug delivery systems for oral administration. Conventional dosage forms …

Orodispersible dosage forms: Biopharmaceutical improvements and regulatory requirements

F Cilurzo, UM Musazzi, S Franzé, F Selmin… - Drug discovery today, 2018 - Elsevier
Highlights•Orodisperisible dosage forms improve the patient's compliance and/or
adherence.•Bioavailability must take in consideration the possible pre-gastric …

Mechanical characteristics of orally disintegrating films: Comparison of folding endurance and tensile properties

Y Takeuchi, N Ikeda, K Tahara, H Takeuchi - International Journal of …, 2020 - Elsevier
The tensile test is the most widely used method for testing the mechanical characteristics of
orally disintegrating films (ODFs). The other available test is the folding endurance (FE) test …

Preparation and evaluation of oral dispersible strips of teneligliptin hydrobromide for treatment of diabetes mellitus

VR Malviya, MG Tawar - International Journal of Pharmaceutical …, 2020 - ijpsnonline.com
The objective of the present study was to formulate the oral dispersible film of teneligliptin
hydrobromide using Pullulan as a polymer and to evaluate it with the different parameters …

Vitamin B12-loaded chitosan-based nanoparticle-embedded polymeric nanofibers for sublingual and transdermal applications: Two alternative application routes for …

E Guler, HB Yekeler, G Parviz, S Aydin… - International Journal of …, 2024 - Elsevier
Alzheimer's disease (AD) is a neurodegeneration type that is biologically recognizable via β-
amyloid plaques and tau neurofibril tangles. Global estimation for the total count of …

Overview about oral films in mental disorders

P Batista, M Pintado, P Oliveira-Silva - Pharmaceuticals, 2023 - mdpi.com
Mental disorders are increasing worldwide, and efforts have been developed by
multidisciplinary research groups to combine knowledge from different areas such as …

Chitosan nanofilm and electrospun nanofiber for quick drug release in the treatment of Alzheimer's disease: In vitro and in vivo evaluation

K AnjiReddy, S Karpagam - International journal of biological …, 2017 - Elsevier
Chitosan micro sized ODF (CBF), chitosan nano sized ODF (CNF) and chitosan nanofiber
(CNfib) were prepared to release the donepezil drug quickly for Alzheimer's disease. CNF …

Formulation, characterization, optimization, and in-vivo performance of febuxostat self-nano-emulsifying system loaded sublingual films

BA Habib, AS Abd El-Samiae, BM El-Houssieny… - Drug Delivery, 2021 - Taylor & Francis
Febuxostat (FXS) is a potent antigout drug with poor water solubility and relative high first-
pass effect leading to moderate oral bioavailability (< 49%). This study aimed to increase …

Anti-solvent precipitation method coupled electrospinning process to produce poorly water-soluble drug-loaded orodispersible films

Q Song, X Guo, Y Sun, M Yang - Aaps Pharmscitech, 2019 - Springer
Orodispersible films (ODFs) are more convenient for paediatric and geriatric patients to take
as compared to conventional tablets and capsules. Electrospinning has recently been …

Frovatriptan loaded hydroxy propyl methyl cellulose/treated chitosan based composite fast dissolving sublingual films for management of migraine

H Singh, YP Singla, RS Narang, D Pandita… - Journal of Drug Delivery …, 2018 - Elsevier
We aimed to prepare frovatriptan succinate monohydrate (FSM) loaded sublingual films to
provide direct entry of FSM into systemic circulation by escaping first-pass effect and thus …