Abstract Interleukin 17 (IL17) is a cytokine involved in immune regulation and has been
increasingly recognized for its role in cancer progression. This systematic review aims to …

The major underlying cause for the high mortality rate in colorectal cancer (CRC) relies on
its drug resistance, to which intratumor heterogeneity (ITH) contributes substantially. CRC …

The clinical significance and comprehensive characteristics of chemokines and chemokine
receptors in female patients with advanced colorectal adenocarcinoma have not ever been …

Locally advanced rectal cancer (LARC) presents a challenge in identifying molecular
markers linked to the response to neoadjuvant chemoradiotherapy (nCRT). This study …

Abstract Doublecortin‐like kinase 1 (DCLK1) is a putative cancer stem cell marker, a
promising diagnostic and prognostic maker for malignant tumors and a proposed driver …

Oral squamous cell carcinoma (OSCC) is the most invasive oral malignancy in adults and is
associated with a poor prognosis. Accurate prognostic models are urgently needed …

Background/Aim: Currently, the impact of diabetes mellitus (DM) on rectal cancer patients is
complex and just partly elucidated. The purpose of this study was to investigate the impact of …

Background Understanding the molecular features associated with response to neoadjuvant
chemoradiotherapy is an unmet clinical need in locally advanced rectal cancer (LARC). The …

Colorectal cancer (CRC) is the third most common malignant cancer worldwide with the
second highest mortality. Gut microbiota can educate the tumor microenvironment (TME) …

Simple Summary Tackling the current dilemma of colorectal cancer resistance to
immunotherapy is puzzling and requires novel therapeutic strategies to emerge. However …