Malaria presents a diagnostic challenge to laboratories in most countries. Endemic malaria,
population movements, and travelers all contribute to presenting the laboratory with …

The replacement of conventional antimalarial drugs with high-cost, artemisinin-based
alternatives has created a gap in the successful management of malaria. This gap reflects …

Artemisin combination therapy (ACT) is the main treatment option for malaria, which is
caused by the intracellular parasite Plasmodium. However, increased resistance to ACT …

Malaria is a global health problem, responsible for nearly 3 million deaths each year, and on
the increase worldwide. Improvements in malaria diagnostics should facilitate the …

Accurate diagnostic tests have a key role in patient management and the control of most
infectious diseases. Unfortunately, in many developing countries, clinical care is often …

Evaluation of rapid diagnostic tests: malaria | Nature Reviews Microbiology Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited …

The persistence of parasite histidine-rich protein 2 (HRP2) in the circulation after parasite
clearance has been considered a drawback for rapid diagnostic tests (RDTs) targeting …

Over the past five decades, the drug resistance of Plasmodium falciparum has become an
issue of utmost concern. At the same time, in vitro assays for assessing antimalarial drug …

Background The discovery of malaria transmission-blocking compounds is seen as key to
malaria elimination strategies and gametocyte-screening platforms are critical filters to …

Abstract Background. In Africa, fever is often treated presumptively as malaria, resulting in
misdiagnosis and the overuse of antimalarial drugs. Rapid diagnostic tests (RDTs) for …