Inter-individual variability in drug response, be it efficacy or safety, is common and likely to
become an increasing problem globally given the growing elderly population requiring …

Physicians, policymakers, and researchers are increasingly focused on finding ways to
decrease opioid use and overdose in the United States both of which have sharply …

Objectives To provide national estimates of the number and clinical and economic burden of
medication errors in the National Health Service (NHS) in England. Methods We used UK …

Cytochrome P450 2D6 (CYP2D6) is a critical pharmacogene involved in the metabolism of~
20% of commonly used drugs across a broad spectrum of medical disciplines including …

Adverse drug reactions (ADRs) remain a challenge in modern healthcare, particularly given
the increasing complexity of therapeutics, an ageing population and rising multimorbidity …

The International Conference on Harmonization considers older people a 'special
population', as they differ from younger adults in terms of comorbidity, polypharmacy …

Adverse drug reactions (ADRs) cause considerable mortality and morbidity but no recent
reviews are currently available for the European region. Therefore, we performed a review of …

Adverse drug reactions (ADRs) are unwanted drug effects that have considerable economic
as well as clinical costs as they often lead to hospital admission, prolongation of hospital …

Drug survival reflects a drug's effectiveness, safety, and tolerability. We assessed the drug
survival of biologics used to treat psoriasis in a prospective national pharmacovigilance …

Adverse drug reactions (ADRs) are an important health issue. While prevalence and risk
factors associated with ADRs in the general adult population have been well documented …