Novel antifungals and treatment approaches to tackle resistance and improve outcomes of invasive fungal disease

M Hoenigl, A Arastehfar, MC Arendrup… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …

[HTML][HTML] Antifungal prophylaxis and pre-emptive therapy: When and how?

R Sprute, JA Nacov, D Neofytos, M Oliverio… - Molecular aspects of …, 2023 - Elsevier
The growing pool of critically ill or immunocompromised patients leads to a constant
increase of life-threatening invasive infections by fungi such as Aspergillus spp., Candida …

Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the Infectious Diseases Society of America

TF Patterson, GR Thompson III… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

[HTML][HTML] Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline

AJ Ullmann, JM Aguado, S Arikan-Akdagli… - Clinical Microbiology …, 2018 - Elsevier
Abstract The European Society for Clinical Microbiology and Infectious Diseases, the
European Confederation of Medical Mycology and the European Respiratory Society Joint …

Invasive aspergillosis in solid‐organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice

S Husain, JF Camargo - Clinical transplantation, 2019 - Wiley Online Library
These updated AST‐IDCOP guidelines provide information on epidemiology, diagnosis, and
management of Aspergillus after organ transplantation. Aspergillus is the most common …

Antifungal prophylaxis for prevention of COVID-19-associated pulmonary aspergillosis in critically ill patients: an observational study

S Hatzl, AC Reisinger, F Posch, J Prattes, M Stradner… - Critical Care, 2021 - Springer
Abstract Background Coronavirus disease 19 (COVID-19)-associated pulmonary
aspergillosis (CAPA) emerged as important fungal complications in patients with COVID-19 …

The 2015 International Society for Heart and Lung Transplantation Guidelines for the management of fungal infections in mechanical circulatory support and …

S Husain, A Sole, BD Alexander, S Aslam… - The Journal of Heart …, 2016 - jhltonline.org
The field of cardiothoracic transplantation (CT) has evolved significantly, but infections
remain an important cause of morbidity and mortality, particularly fungal infections (FIs). The …

Immune correlates of protection in human invasive aspergillosis

JF Camargo, S Husain - Clinical infectious diseases, 2014 - academic.oup.com
An improved understanding of the pathogenesis of Aspergillus infections has facilitated the
identification of host biomarkers that, if validated in well-designed prospective studies, could …

10 years of prophylaxis with nebulized liposomal amphotericin B and the changing epidemiology of Aspergillus spp. infection in lung transplantation

M Peghin, V Monforte, MT Martin‐Gomez… - Transplant …, 2016 - Wiley Online Library
The aim of this study was to assess the outcome and tolerability of prophylactic nebulized
liposomal amphotericin B (n‐LAB) in lung transplant recipients (LTR) and the changing …

Clinical risk factors for invasive aspergillosis in lung transplant recipients: results of an international cohort study

CA Aguilar, B Hamandi, C Fegbeutel, FP Silveira… - The Journal of Heart and …, 2018 - Elsevier
BACKGROUND Invasive aspergillosis (IA) is a frequent complication in lung transplant
recipients (LTRs). Clinical risk factors for IA have not been fully characterized, especially in …