Going global by adapting local: A review of recent human adaptation

S Fan, MEB Hansen, Y Lo, SA Tishkoff - Science, 2016 - science.org
The spread of modern humans across the globe has led to genetic adaptations to diverse
local environments. Recent developments in genomic technologies, statistical analyses, and …

Lactose intolerance, dairy avoidance, and treatment options

A Szilagyi, N Ishayek - Nutrients, 2018 - mdpi.com
Lactose intolerance refers to symptoms related to the consumption of lactose-containing
dairy foods, which are the most common source for this disaccharide. While four causes are …

On the origin of obesity: identifying the biological, environmental and cultural drivers of genetic risk among human populations

A Qasim, M Turcotte, RJ de Souza… - Obesity …, 2018 - Wiley Online Library
Genetic predisposition to obesity presents a paradox: how do genetic variants with a
detrimental impact on human health persist through evolutionary time? Numerous …

Population genomics of rapid adaptation by soft selective sweeps

PW Messer, DA Petrov - Trends in ecology & evolution, 2013 - cell.com
Organisms can often adapt surprisingly quickly to evolutionary challenges, such as the
application of pesticides or antibiotics, suggesting an abundant supply of adaptive genetic …

On the evolution of lactase persistence in humans

L Ségurel, C Bon - Annual review of genomics and human …, 2017 - annualreviews.org
Lactase persistence—the ability of adults to digest the lactose in milk—varies widely in
frequency across human populations. This trait represents an adaptation to the …

How culture shaped the human genome: bringing genetics and the human sciences together

KN Laland, J Odling-Smee, S Myles - Nature Reviews Genetics, 2010 - nature.com
Researchers from diverse backgrounds are converging on the view that human evolution
has been shaped by gene–culture interactions. Theoretical biologists have used population …

The genetics of human adaptation: hard sweeps, soft sweeps, and polygenic adaptation

JK Pritchard, JK Pickrell, G Coop - Current biology, 2010 - cell.com
There has long been interest in understanding the genetic basis of human adaptation. To
what extent are phenotypic differences among human populations driven by natural …

Retrospective and prospective perspectives on zoonotic brucellosis

E Moreno - Frontiers in microbiology, 2014 - frontiersin.org
Members of the genus Brucella are pathogenic bacteria exceedingly well adapted to their
hosts. The bacterium is transmitted by direct contact within the same host species or …

African genetic diversity: implications for human demographic history, modern human origins, and complex disease mapping

MC Campbell, SA Tishkoff - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Comparative studies of ethnically diverse human populations, particularly in Africa, are
important for reconstructing human evolutionary history and for understanding the genetic …

[图书][B] Sense and nonsense: Evolutionary perspectives on human behaviour

KN Laland, GR Brown - 2011 - books.google.com
Evolutionary theory is one of the most wide-ranging and inspiring of scientific ideas. It offers
a battery of methods that can be used to interpret human behaviour. But the legitimacy of this …